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    1. Central research Institute of Epidemiology of Rospotrebnadzor RF (Moscow, Russian Federation)
    2. Federal STATE institution of science «MNIIEM named after G.N. Gabrichevskiy» of Rospotrebnadzor (Moscow, Russian Federation)
    3. FSBI «Research Institute of Virology D.I. Ivanovsky» Ministry of Health of Russia (Moscow, Russian Federation)
    4. First MSMU of I. M. Sechenov (Moscow, Russian Federation)

    Keywords:acute intestinal infections,therapy

    Abstract:The article presents the results of an experimental study of pathogenetic therapy of acute intestinal infections on the example of the biological model. Gelatin Tanat and dioctahedral smectite have a protective effect on the mucosa of the colon with a viral intestinal infection. This is manifested by a reduction in the severity of acute enteritis. The results of the experiment convincingly demonstrated the benefits of early appointment cytoprotective medicine and sorbents in the treatment of acute intestinal infections.

      1. Сведения об инфекционных и паразитарных заболеваниях (Форма 1) за январь-июнь 2015. www.rospotrebnadzor.ru (http://www.rospotrebnadzor.ru/activities/statistical-materials/statictic_details.php?ELEMENT_ID=3919). Вход 10.08.2015.
      2. Малеев В. В., Горелов А. В., Усенко Д. В., Кулешов К. И. Актуальные проблемы, итоги и перспективы изучения острых кишечных инфекций // Эпидемиология и инфекционные болезни. 2014. № 1. С. 4.
      3. Горелов А. В. Терапия острых кишечных инфекций у детей в современных условиях // Вопросы современной педиатрии. № 4/том 3/2004. С. 72-78.
      4. Haslam E. Natural polyphenols (vegetable tannins) as drugs: possible modes of action. J Nat Prod 1996. 59: 205-215.
      5. Miguel Angel, Alonso Cohen, Marco Di Fulvio. Патент EP 2526939 A1. Gelatine tannate and associations thereof for use in the treatment of inflammatory gastrointestinal diseases.
      6. Frasca G, Cardile V, Puglia C, Bonina C, Bonina F. Gelatin tannate reduces the proinflammatory effects of lipopolysaccharide in human intestinal epithelial cells. Clin Exp Gastroenterol. 2012;5:61-7.
      7. Esteban Carretero J, Durbán Reguera F, López-Argüeta Alvarez S, López Montes J. A comparative analysis of response to vs. ORS + gelatin tannate pediatric patients with acute diarrhea. Rev Esp Enferm Dig 2009; 101:41-48.
      8. Marek Ruszczyński, Magdalena Urbańska, and Hania Szajewska. Gelatin tannate for treating acute gastroenteritis: a systematic review. Ann Gastroenterol. 2014; 27 (2): 121-124.
      9. Allegrini A, Costantini M. Gelatine Tannate for the Treatment of Acute Diarrhoea in Adults. J Gastrointest Digest Sys 2012. 2:110.
      10. Meloni M et al., New insights into the mechanism of action of Gelatine Tanate for Acute diarrhoea, protection against bacterial infection. Presented at the GFHGHP Congress, March 2012. Nantes, France.
      11. Бландова З. К., Душкин В. А. и др. Линии лабораторных животных для медико-биологических исследований. - М. Наука, 1983 г., с172.
      12. Руководство по лабораторным животным и альтернативным моделям в биомедицинских технологиях под редакцией: Н. Н. Каркищенко и С. В. Грачева. Москва - 2010. 344 с.
      13. Michael S. D. Agus, Tom Jaksic. Nutritional support of the critically ill child // Current Opinion in Pediatrics. 2002; 14: 470-481.
     


    Full text is published :
    Ploskireva A.A.,Ruzhentsova T.A.,Shcherbakov I.T.,Isaeva E.I. et al. CYTOPROTECTIVE ASPECTS OF PATHOGENETIC THERAPY OF ACUTE INTESTINAL INFECTIONS. Experimental and Clinical Gastroenterology Journal. 2016;125(01):65-73
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