Submission of the manuscript is online via e-mail
ecgarticle@gmail.com or
cholerez@mail.ru

Tel: +7 903 250 5288

Editorial Correspondence e-mail
gastrossr@gmail.com


Publishing, Subscriptions, Sales and Advertising, Correspondence e-mail
journal@cniig.ru

Tel: +7 917 561 9505

SCImago Journal & Country Rank

    1. Omsk State Medical University (Omsk, Russian Federation)

    Keywords:ulcerative colitis,prevalence,risk factors

    Abstract:Ulcerative colitis (UC) is idiopathic chronic relapsing inflammational disorder of the colon. In recent years, there are new details appeared about the prevalence and development of UC. In the present review article sanctified influence of factors such as patient age, sex, influence of heredity, environmental factors, behavioral factors. Also considered a possible protective effect of the microorganism Helicobacter pylori against inflammatory bowel disease. The article also discussed the possible involvement of viruses, medications, nutritional factors, as well as psycho-emotional factors on the risk of formation of ulcerative colitis.

      1. Клинические рекомендации по диагностике и лечению взрослых больных язвенным колитом. Разработаны экспертной комиссией «Российской гастроэнтерологической ассоциации». 2013.
      2. Bernstein C. N., Wajda A, Svenson L.W, et al. The epidemiology of inflammatory bowel disease in Canada: a population-based study. // Am J Gastroenterol. - 2006. - Vol. 101. - P. 1559-1568.
      3. Loftus C. G., Loftus E. V., Harmsen W. S., et al. Update on the incidence and prevalence of Crohn’s disease and ulcerative colitis in Olmsted County, Minnesota, 1940-2000.// Inflamm Bowel Dis. - 2007. - Vol.13. - P. 254-261.
      4. Jacobsen B. a, Fallingborg J., Rasmussen H. H., et al. Increase in incidence and prevalence of inflammatory bowel disease in northern Denmark: a population-based study, 1978-2002. // Eur J Gastroenterol Hepatol. - 2006. - Vol. 18. - P. 601-606.
      5. Rönnblom A., Samuelsson S.-M., Ekbom A. Ulcerative colitis in the county of Uppsala 1945-2007: incidence and clinical characteristics. // J Crohns Colitis. - 2010. - Vol. 4. - P. 532-536.
      6. Rubin G. P., Hungin a P., Kelly P. J., et al. Inflammatory bowel disease: epidemiology and management in an English general practice population. // Aliment Pharmacol Ther. - 2000. - Vol. 14. - P. 1553-1559.
      7. Gheorghe C., Pascu O., Gheorghe L., et al. Epidemiology of inflammatory bowel disease in adults who refer to gastroenterology care in Romania: a multicentre study. // Eur J Gastroenterol Hepatol. - 2004. - Vol. 16. - P. 1153-1159.
      8. Salupere R. Inflammatory bowel disease in Estonia: a prospective epidemiologic study 1993-1998. // World J Gastroenterol. - 2001. - Vol. 7. - P. 387-388.
      9. Asakura K, Nishiwaki Y, Inoue N, Hibi T, Watanabe M, Takebayashi T. Prevalence of ulcerative colitis and Crohn’s disease in Japan. // J Gastroenterol. - 2009. - Vol. 44. - P. 659-665.
      10. Niriella MA, De Silva AP, Dayaratne AH, Ariyasinghe MH, Navarathne MM, Peiris RS, Samarasekara DN, Satharasinghe RL, Rajindrajith S, Dassanayake AS, et al. Prevalence of inflammatory bowel disease in two districts of Sri Lanka: a hospital based survey. // BMC Gastroenterol. - 2010. - Vol.10. - P. 32.
      11. Cosnes J, Gower-Rousseau C, Seksik P, Cortot A. Epidemiology and natural history of inflammatory bowel diseases. // Gastroenterology. - 2011. - Vol. 140. - P. 1785-1794.
      12. Appleyard CB, Hernández G, Rios-Bedoya CF. Basic epidemiology of inflammatory bowel disease in Puerto Rico. // Inflamm Bowel Dis. - 2004. - Vol. 10. - P. 106-111.
      13. Lakatos L, Mester G, Erdelyi Z, Balogh M, Szipocs I, Kamaras G, Lakatos PL. Striking elevation in incidence and prevalence of inflammatory bowel disease in a province of western Hungary between 1977-2001. // World J Gastroenterol. - 2004. - Vol. 10. - P. 404-409.
      14. Yang SK, Hong WS, Min YI, Kim HY, Yoo JY, Rhee PL, Rhee JC, Chang DK, Song IS, Jung SA, et al. Incidence and prevalence of ulcerative colitis in the Songpa-Kangdong District, Seoul, Korea, 1986-1997. // J Gastroenterol Hepatol. - 2000. - Vol. 15. - P. 1037-1042.
      15. Evans JG. Trends in mortality from ulcerative colitis in England and Wales. // Gut. - 1971. - Vol. 12. - P. 119-122.
      16. Gyde S, Prior P, Dew MJ, Saunders V, Waterhouse JA, Allan RN. Mortality in ulcerative colitis. // Gastroenterology. - 1982. - Vol. 83. - P. 36-43.
      17. Manninen P, Karvonen AL, Huhtala H, Rasmussen M, Salo M, Mustaniemi L, Pirttiniemi I, Collin P. Mortality in ulcerative colitis and Crohn’s disease. A population-based study in Finland. // J Crohns Colitis. - 2012. Vol.6. - P. 524-528.
      18. Jess T, Gamborg M, Munkholm P, Sørensen TI. Overall and cause-specific mortality in ulcerative colitis: meta-analysis of population-based inception cohort studies. // Am J Gastroenterol. - 2007. - Vol.102. - P. 609-617.
      19. Prideaux L, Kamm MA, De Cruz PP, Chan FK, Ng SC. Inflammatory bowel disease in Asia: a systematic review. // J Gastroenterol Hepatol. - 2012. - Vol. 27. - P. 1266-1280.
      20. Bernstein CN, Rawsthorne P, Cheang M, et al. A population-based case control study of potential risk factors for IBD. // Am J Gastroenterol. - 2006. - Vol. 101. - P. 993-100.
      21. Barreiro-de Acosta M, Magro F, Carpio D, Lago P, Echarri A, Cotter J, Pereira S, Gonçalves R, Lorenzo A, Carvalho L, et al. Ulcerative colitis in northern Portugal and Galicia in Spain. // Inflamm Bowel Dis. - 2010. - Vol. 16. - P. 1227-1238.
      22. Betteridge JD, Armbruster SP, Maydonovitch C, Veerappan GR. Inflammatory bowel disease prevalence by age, gender, race, and geographic location in the U.S. military health care population. // Inflamm Bowel Dis. - 2013. - Vol. 19. - P. 1421-1427.
      23. Orholm M., Munkholm P., Langholtz E.et al. Familial occurrence of inflammatory bowel disease. // N. Engl. J. Med. - 1999. - Vol. 334. - P. 84-88.
      24. Childers RE, Eluri S, Vazquez C, Weise RM, Bayless TM, Hutfless S. J. Family history of inflammatory bowel disease among patients with ulcerative colitis: a systematic review and meta-analysis. // Crohns Colitis. - 2014 Nov. - Vol. 8(11). - P. 1480-97. doi: 10.1016/j.crohns.2014.05.008. Epub 2014 Jun 26.
      25. Henriksen M, Jahnsen J, Lygren I, Vatn MH, Moum B. Are there any differences in phenotype or disease course between familial and sporadic cases of inflammatory bowel disease? Results of a population-based follow-up study. // Am J Gastroenterol. - 2007. - Vol. 102. - P. 1955-1963.
      26. Wallace KL, Zheng LB, Kanazawa Y, Shih DQ. Immunopathology of inflammatory bowel disease. // World J Gastroenterol. - 2014. - Vol. 20. - P. 6-21.
      27. Gent AE, Hellier MD, Grace RH, Swarbrick ET, Coggon D. Inflammatory bowel disease and domestic hygiene in infancy. // Lancet. - 1994. - Vol. 343. - P. 766-767.
      28. Главнов П. В., Лебедева Н. Н., Кащенко В. А., Варзин С. А. Язвенный колит и болезнь Крона. Современное состояние проблемы этиологии, ранней диагностики и лечения (обзор литературы). Вестник СПбГУ. 2015; 4: 48-72
      29. Koloski NA, Bret L, Radford-Smith G. Hygiene hypothesis in inflammatory bowel disease: a critical review of the literature. // World J Gastroenterol. - 2008. - Vol. 14. - P. 165-173.
      30. Baron S, Turck D, Leplat C, Merle V, Gower-Rousseau C, Marti R, Yzet T, Lerebours E, Dupas JL, Debeugny S, Salomez JL, Cortot A, Colombel JF. Environmental risk factors in paediatric inflammatory bowel diseases: a population based case control study. // Gut. - 2005. - Vol. 54. - P. 357-363.
      31. Бодрягина Е. С., Абдулганиева Д. И., Одинцова А. Х. Клинико-эпидемиологические показатели воспалительных заболеваний кишечника по Республике Татарстан. Лечащий врач. 2013.
      32. Carpio D, Barreiro-de Acosta M, Echarri A, Pereira S, Castro J, Ferreiro R, Lorenzo A, Group E. Influence of urban/rural and coastal/inland environment on the prevalence, phenotype, and clinical course of inflammatory bowel disease patients from northwest of Spain: a cross-sectional study. // Eur J Gastroenterol Hepatol. - 2015. -Vol.27. - P. 1030-7.
      33. Malekzadeh F, Alberti C, Nouraei M, Vahedi H, Zaccaria I, Meinzer U, Nasseri-Moghaddam S, Sotoudehmanesh R, Momenzadeh S, Khaleghnejad R, Rashtak S, Olfati G, Malekzadeh R, Hugot JP. Crohn’s disease and early exposure to domestic refrigeration. // PLoS One. - 2009. - Vol.4. - P. e4288.
      34. Shepherd, B., Schwartz D. A. Inflammatory bowel disease: diagnostic and treatment options. // Hosp. Physician. - 2005. - Vol. 41(10). - P. 11-19.
      35. Calkins BM. A meta-analysis of the role of smoking in inflammatory bowel disease. // Dig Dis Sci. - 1989. - Vol. 34. - P. 1841-1854.
      36. Odes HS, Fich A, Reif S, Halak A, Lavy A, Keter D, Eliakim R, Paz J, Broide E, Niv Y, et al. Effects of current cigarette smoking on clinical course of Crohn’s disease and ulcerative colitis. // Dig Dis Sci. - 2001. - Vol. 46. - P. 1717-1721.
      37. Aldhous MC, Drummond HE, Anderson N, Baneshi MR, Smith LA, Arnott ID, Satsangi J. Smoking habit and load influence age at diagnosis and disease extent in ulcerative colitis. // Am J Gastroenterol. - 2007. - Vol. 102. - P. 589-597.
      38. Rutgeerts P, D’Haens G, Hiele M, Geboes K, Vantrappen G. Appendectomy protects against ulcerative colitis. // Gastroenterology. - 1994. - Vol. 106. - P. 1251-1253.
      39. Koutroubakis IE, Vlachonikolis IG, Kouroumalis EA. Role of appendicitis and appendectomy in the pathogenesis of ulcerative colitis: a critical review. // Inflamm Bowel Dis. - 2002. - Vol. 8. - P. 277-286.
      40. Florin TH, Pandeya N, Radford-Smith GL. Epidemiology of appendicectomy in primary sclerosing cholangitis and ulcerative colitis: its influence on the clinical behaviour of these diseases. // Gut. - 2004. - Vol. 53. - P. 973-979.
      41. Radford-Smith GL, Edwards JE, Purdie DM, Pandeya N, Watson M, Martin NG, Green A, Newman B, Florin TH. Protective role of appendicectomy on onset and severity of ulcerative colitis and Crohn’s disease. // Gut. - 2002. - Vol. 51. - P. 808-813.
      42. Luther J, Dave M, Higgins PD, Kao JY. Association between Helicobacter pylori infection and inflammatory bowel disease: a meta-analysis and systematic review of the literature. // Inflamm Bowel Dis. - 2010. - Vol. 16. - P. 1077-1084.
      43. Wu XW, Ji HZ, Yang MF, Wu L, Wang FY. Helicobacter pylori infection and inflammatory bowel disease in Asians: a meta-analysis. // World J Gastroenterol. - 2015. - Vol. 21. - P. 4750-4756.
      44. Linton MS, Kroeker K, Fedorak D, Dieleman L, Fedorak RN. Prevalence of Epstein-Barr Virus in a population of patients with inflammatory bowel disease: a prospective cohort study. // Aliment Pharmacol Ther. - 2013. - Vol. 38. - P. 1248-1254.
      45. Ng SC, Woodrow S, Patel N, Subhani J, Harbord M. Role of genetic and environmental factors in British twins with inflammatory bowel disease. // Inflamm Bowel Dis. - 2012. - Vol. 18. - P. 725-736.
      46. Sipponen T, Turunen U, Lautenschlager I, Nieminen U, Arola J, Halme L. Human herpesvirus 6 and cytomegalovirus in ileocolonic mucosa in inflammatory bowel disease. // Scand J Gastroenterol. - 2011 - Vol. 46. - P. 1324-1333.
      47. Felder JB, Korelitz BI, Rajapakse R, Schwarz S, Horatagis AP, Gleim G. Effects of nonsteroidal antiinflammatory drugs on inflammatory bowel disease: a case-control study. // Am J Gastroenterol. - 2000. - Vol. 95. - P. 1949-1954.
      48. Kvasnovsky CL, Aujla U, Bjarnason I. Nonsteroidal anti-inflammatory drugs and exacerbations of inflammatory bowel disease. // Scand J Gastroenterol. - 2015. - Vol. 50. - P. 255-263.
      49. Berg DJ, Zhang J, Weinstock JV, Ismail HF, Earle KA, Alila H, Pamukcu R, Moore S, Lynch RG. Rapid development of colitis in NSAID treated IL-10-deficient mice. // Gastroenterology. - 2002. - Vol. 123. - P. 1527-1542.
      50. Cornish JA, Tan E, Simillis C, Clark SK, Teare J, Tekkis PP. The risk of oral contraceptives in the etiology of inflammatory bowel disease: a meta-analysis. // Am J Gastroenterol. - 2008. - Vol. 103. - P. 2394-2400.
      51. Hviid A, Svanstrom H, Frisch M. Antibiotic use and inflammatory bowel diseases in childhood. // Gut. - 2011. - Vol. 60. - P. 49-54.
      52. Hildebrand H, Malmborg P, Askling J, Ekbom A, Montgomery SM. Early-life exposures associated with antibiotic use and risk of subsequent Crohn’s disease. // Scand J Gastroenterol. - 2008. - Vol. 43. - P. 961-966.
      53. Seth D. Crockett, MD, Carol Q. Porter, BS, Christopher F. Martin, MSPH, Robert S. Sandler, MD, MPH, and Michael D. Kappelman, MD, MPH. Isotretinoin Use and the Risk of Inflammatory Bowel Disease: A Case Control Study. // Am J Gastroenterol. - 2010 Sep. - Vol. 105(9). - P. 1986-1993.
      54. Alhusayen RO, Juurlink DN, Mamdani MM, Morrow RL, Shear NH, Dormuth CR, Canadian Drug Safety and Effectiveness Research Network. Isotretinoin use and the risk of inflammatory bowel disease: a population-based cohort study. // J Invest Dermatol. - 2013 Apr. - Vol. 133(4). - P. 907-12.
      55. Geerling BJ, Dagnelie PC, Badart-Smook A, Russel MG, Stockbrugger RW, Brummer RJ. Diet as a risk factor for the development of ulcerative colitis. // Am J Gastroenterol. - 2000. - Vol. 95. - P. 1008-1013.
      56. Ananthakrishnan AN, Khalili H, Konijeti GG, Higuchi LM, de Silva P, Fuchs CS, Willett WC, Richter JM, Chan AT. Long-term intake of dietary fat and risk of ulcerative colitis and Crohn’s disease. // Gut. - 2014. - Vol. 63. - P. 776-784.
      57. Lee JY, Zhao L, Youn HS, Weatherill AR, Tapping R, Feng L, Lee WH, Fitzgerald KA, Hwang DH. Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1. // J Biol Chem. - 2004. - Vol. 279. - P. 16971-16979.
      58. Sakamoto N, Kono S, Wakai K, Fukuda Y, Satomi M, Shimoyama T, Inaba Y, Miyake Y, Sasaki S, Okamoto K, Kobashi G, Washio M, Yokoyama T, Date C, Tanaka H. Epidemiology Group of the Research Committee on Inflammatory Bowel Disease in Japan. Dietary risk factors for inflammatory bowel disease: a multicenter case-control study in Japan. // Inflamm Bowel Dis. - 2005. - Vol. 11. - P. 154-163.
      59. Li F, Liu X, Wang W, Zhang D. Consumption of vegetables and fruit and the risk of inflammatory bowel disease: a meta-analysis. // Eur J Gastroenterol Hepatol. - 2015. -Vol. 27. - P. 623-633.
      60. Galvez J, Rodriguez-Cabezas ME, Zarzuelo A. Effects of dietary fiber on inflammatory bowel disease. // Mol Nutr Food Res. - 2005. - Vol. 49. - P. 601-608.
      61. Maiko Sasaki, Jan-Michael A. Klapproth. The Role of Bacteria in the Pathogenesis of Ulcerative Colitis. // J. Signal. Transduct. - 2012. - Vol, 2012. - P. 704953. Published online 2012 April 24
      62. Maunder RG, Levenstein S. The role of stress in the development and clinical course of inflammatory bowel disease: epidemiological evidence. // Curr Mol Med. - 2008. - Vol. 8. - P. 247-252.
      63. Mawdsley JE, Rampton DS. Psychological stress in IBD: new insights into pathogenic and therapeutic implications. // Gut. - 2005. - Vol. 54. - P. 1481-1491.
      64. Bonaz BL, Bernstein CN. Brain-gut interactions in inflammatory bowel disease. // Gastroenterology. - 2013. - Vol. 144. - P. 36-49.
      65. Ali, T. et al. Assessment of the relationship between quality of sleep and disease activity in inflammatory bowel disease patients.// Inflamm. Bowel Dis. - 2013. - Vol. 19. - P. 2440-2443.
     


    Full text is published :
    Akhmedov V.A., Bikbavova G.R., Emeliyanova U.A. MODERN VIEWS ON PREVALENCE, RISK FACTORS AND CAUSES OF ULCERATIVE COLITIS. Experimental and Clinical Gastroenterology Journal. 2017;146(10):110-115
    Read & Download full text