Submission of the manuscript is online via e-mail
ecgarticle@gmail.com or
cholerez@mail.ru

Tel: +7 903 250 5288

Editorial Correspondence e-mail
gastrossr@gmail.com


Publishing, Subscriptions, Sales and Advertising, Correspondence e-mail
journal@cniig.ru

Tel: +7 917 561 9505

SCImago Journal & Country Rank

    1. North-Western State Medical University named after I. I. Mechnikov (St. Petersburg, Russian Federation)
    2. Scientific Research Institute named after N. N. Petrov (St. Petersburg, Russian Federation)
    3. Leningrad Regional Clinical Hospital (St. Petersburg, Russian Federation)
    4. I. P. Pavlov First Saint Petersburg State Medical University (St. Petersburg, Russian Federation)

    Keywords:Aspergillus,invasive aspergillosis,mycosis of the digestive tract,Aspergillus

    Abstract:Invasive aspergillosis is actual problem in patients with hematological malignancies. Lungs damage develops most often. Digestive tract involvement occurs in 1.3 % of patients with invasive aspergillosis, mainly as a result of hematogenous dissemination. Risk factors are lymphocytopenia, neutropenia, corticosteroid therapy, and staying in the ICU. The most frequently we identified liver involvement (63 %), rarely - intestines (25 %) and esophagus (12 %). Infection is characterized by a high 12-week mortality - 63 %. Early diagnosis, voriconazole therapy and surgical treatment are necessary.

      1. De Pauw B., Walsh T. J., Donnelly J. P., et al. Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer / Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group // Clinical Infectious Diseases. - 2008. - Vol. 46, № 12. - P. 1813-21.
      2. Климко Н. Н., Шадривова О. В., Хостелиди С. Н. и др. Инвазивный аспергиллез: результаты многоцентрового исследования. Онкогематология. - 2014. - № 2. - С. 13-19.
      3. Eggimann P., Chevrolet J.-C., Starobinski M. et al. Primary Invasive Aspergillosis of the Digestive Tract: Report of Two Cases and Review of the Literature. Infection. - 2006. - Vol. 34, № 6. - P. 333-338.
      4. Bizet J., Cooper C. J., Zuckerman M. J., Torabi A., Mendoza-Ladd A. A bleeding colonic ulcer from invasive Aspergillus infection in an immunocompromised patient: a case report. Journal of Medical Case Reports. - 2014. - 8:407. - http://www.jmedicalcasereports.com/content/8/1/407.
      5. Karaman I., Karaman A., Boduroglu E. C., et al. Invasive Aspergillus infection localized to the gastric wall: report of a case. Surgery Today. - 2013. - Vol. 43. - P. 682-684.
      6. González-Vicent M., Díaz M. A., Colmenero I., et al. Primary gastrointestinal aspergillosis after autologous peripheral blood progenitor cell transplantation: an unusual presentation of invasive aspergillosis // Transplant Infectious Disease. - 2008. - Vol.10. - P. 193-196.
      7. Диагностика и лечение микозов в отделениях реанимации и интенсивной терапии. Российские рекомендации / ред. Н. Н. Климко - М: Фармтек. - 2015. - 95 с.
      8. Patterson T. F., Thompson G. R., Denning D. W. Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases. - 2016. - Vol.63, № 6. - DOI: 10.1093/cid/ciw326
     


    Full text is published :
    Shadrivova O.V., Shevyakov M.A., Desyatik E.A., Bogomolova T.S. INVASIVE ASPERGILLOSIS OF THE DIGESTIVE TRACT: PROSPECTIVE STUDY RESULTS AND CLINICAL CASE OF COLON ASPERGILLOSIS. Experimental and Clinical Gastroenterology Journal. 2017;146(10):124-127
    Read & Download full text