1. The Federal State Budgetary Scientific Institution «Petrovsky National Research Center of Surgery» (Moscow, Russian Federation)

Keywords:dysplasia of epithelium,intestinal metaplasia,columnar-celled metaplasia,argon-plasma coagulation,endoscopic mucosal resection

Abstract:The aim of the study is the rationalizing of the strategy change of endoscopic diagnostics, follow-up and treatment of patients with Barrett’s esophagus. From 2007 to 2015 Barrett’s mucosa has been defined during upper endoscopy in 111 patients of the main group. Another 12 patients with Barrett’s esophagus were followed-up from 1995 to 2010-2015. Endoscopic argon-plasma coagulation of the abnormal areas of the Barrett’s mucosa was performed in 17, endoscopic mucosal resection in 2 patients. The result was the recovery of stratified squamous esophageal epithelium. The remaining 92 patients were treated only by drug therapy. None of the 111 patients in the main group and as well as 12 patients followed-up since 1995, had any progression of Barrett’s esophagus of any length metaplasia segment, nor on the expression of intestinal metaplasia or dysplasia. Extensive experience in endoscopic diagnostics of esophageal diseases and the use of high resolution and high definition endoscopes with a variety of additional features are the base of a correct diagnosis of Barrett’s esophagus.

• References total 8 ⇓ :: .
  1. Koppert L., Wijnhoven B., van Dekken H., Tilanus H., Dinjens W. The molecular biology of esophageal adenocarcinoma. J Surg Oncol (2005) 92 (3): 169-90. PMID 16299787.
  2. Levine D.S., Blount P. L., Rudolph R. E., et al. Safety of a systematic endoscopic biopsy protocol in patients with Barrett’s esophagus. Am J Gastroenterol 2000; 95: 1152-7
  3. Май Андреа. Эндоскопическая диагностика и лечение пищевода Барретта с неоплазией и без. Эндоскопия 4, 2012: 11-16.
  4. Aoki T., Kawaura Y., Kouzu T., et al. Report of the Research Committee on the Definition of Barrett’s Esophagus (Epithelium) [in Japanese]. In: Sugimachi K, editor. Reports of the research committees of The Japanese Society for Esophageal Diseases. Chiba: Japanese Society of Esophageal Diseases; 2000: 20-23.
  5. Choi do W., Oh S. N., Baek S. J. et al. Endoscopically observed lower esophageal capillary patterns. Korean J. Intern. Med. - 2002. - Vol. 17, N 4. - P. 245-248.
  6. Ивашкин В.Т., Маев И. В., Трухманов А. С. и др. Клинические рекомендации Российской Гастроэнтерологической Ассоциации по диагностике и лечению пищевода Барретта, 2014.
  7. Vahabzadeh B., Seetharam A. B., Cook M. B., et al. Validation of the Prague C & M criteria for the endoscopic grading of Barrett’s esophagus by gastroenterology trainees: a multicenter study. Gastrointest Endosc 2012; 75: 236-41.
  8. Yousef F., Cardwell C., Cantwell M. M., et al. The incidence of esophageal cancer and highgrade dysplasia in Barrett’s esophagus: a systematic review and meta-analysis. Am J Epidemiol 2008; 168: 237-249.

Full text is published :
Godzhello E.A., Khrustaleva M.V., Bulganina N.A., Shatveryan D.G. et al. MODERN STRATEGY OF BARRETT’S ESOPHAGUS ENDOSCOPIC DIAGNOSTICS, TREATMENT AND FOLLOW-UP. Experimental and Clinical Gastroenterology Journal. 2017;140(04):15-21
Read & Download full text

1. I. M. Sechenov First Moscow State Medical University (Moscow, Russian Federation)
2. Clinical Hospital № 15 named after O. M. Filatov (Moscow, Russian Federation)

Keywords:pancreatitis,acute interstitial pancreatitis,pancreatic necrosis,gastroduodenoscopy

Abstract:Aim: Endoscopic diagnosis of changes in the upper gastrointestinal tract in patients with acute pancreatitis and pancreatic necrosis. Materials and Methods: The results of esophagogastroduodenoscopy (EGD), 238 patients with acute pancreatitis. Patients were divided into two groups: patients with acute pancreatitis (173) and patients with pancreatic necrosis (65). Results: In the group of patients with acute pancreatitis in 71.1 % of patients were registered changes in the mucosa of the upper gastrointestinal tract. A 28.9 % of patients no changes were observed. 11.6 % had changes in the gastric mucosa. 23.1 % of patients had changes in the duodenal mucous membrane. Edema longitudinal fold was found in 31.2 % of all patients, as a result, in 6 % of patients it was impossible to visualize the papilla. In the group of patients with pancreatic necrosis, in 100 % were registered changes in the upper gastrointestinal tract. In 8.5 % of patients was found esophagitis, 32 % had gastric erosive changes, and in 50 % of cases detected gastroduodenitis. Conclusion: Specific treatment aimed at protecting gastrointestinal mucosa is required for all patients with pancreatic necrosis.

• References total 9 ⇓ :: .
  1. Багненко С.Ф., Толстой А. Д., Красногоров В. Д. и др. Острый панкреатит (Протоколы диагностики и лечения). - Анналы хирургической гепатологии, 2006. - Т. 11. - № 1. - с. 60-66.
  2. Бурневич С. З., Куликова В. М., Сергеева Н. А. и др. Диагностика и хирургическое лечение панкреонекроза. - Анналы хирургической гепатологии, 2006. - Т. 11. - № 4. - с. 10-14.
  3. Лысенко М. В., Девятов А. С., Урсов С. В. и др. Острый панкреатит: дифференцированная лечебно-диагностическая тактика. М: Литтерра; 2010; 192с.
  4. Toouli J., Brook-Smith M., Bassi C. et al. Guidelines for the management of acute pancreatitis // J GastroenterolHepatol. 2002; (Suppl 17): S 15-39.
  5. СавельевВ.С.ФилимоновМ.И., Бурневич С. З. Панкреонекрозы. М: Медицинское информационное агенство, 2008.264 с.
  6. Freeman M. L., Werner J., vanSantvoortH.C., Baron T. H. at al. Intervention for necrotizing pancreatitis: summary of a multidisciplinary concensus conference.Pancreas. 2012;41(8): 1176-1194.
  7. Ю.А. Нестеренко, В. В. Лаптев, С. В. Михайлусов. Диагностика и лечение деструктивного панкреатита. М: ООО «Бином - Пресс», 2004;304 с.
  8. Митьков В. В. Практическое руководство по ультразвуковой диагностике. Общая ультразвуковая диагностика, М: Видар - М, 2011, 712с.
  9. А. Е. Котовский, Г. А. Уржумцева, М. В. Яковенко, О. П. Примасюк и др. Изменения слизистой оболочки желудка и двенадцатиперстной кишки при панкреонекрозе., ХIХ Сьезд хирургов 2000, Волгоград, стр. 65.

Full text is published :
Zvereva A.A., Kotovsky A.E., Glebov K.G. ENDOSCOPIC CHANGES IN THE UPPER GASTROINTESTINAL TRACT IN PATIENTS WITH ACUTE PANCREATITIS AND PANCREATIC NECROSIS, TREATMENT AND FOLLOW-UP. Experimental and Clinical Gastroenterology Journal. 2017;140(04):22-26
Read & Download full text

1. Central clinical hospital of Administration of the President of the Russian Federation (Moscow, Russian Federation)

Keywords:Cholangiocarcinoma,cholangioscopy,confocal laser endomicroscopy,obstructive jaundicebile duct stones,pancreatic cancer

Abstract:An analysis of published data on the effectiveness of various methods of diagnosis of obstructive jaundice syndrome, caused by stones and bile duct strictures of various origins. We conducted an analysis of own data on the effectiveness and accuracy cholangioscopy and confocal laser confocal laser endomicroscopy (CLE) in the diagnosis of the causes of biliary obstruction. The efficacy of endoscopic retrograde cholangiopancreatography is considered in combination with additional methods of examination

• References total 20 ⇓ :: .
  1. Миниинвазивные вмешательства в лечении желчнокаменной болезни у больных пожилого и старческого возраста/ Н. И. Глушков и др.// Хирургия. - 2010. - № 10. - С. 53-58;
  2. Cha I. H., Kim J. N., Kim Y. S. Metastatic сommon bile duct cancer from pulmonary adenocarcinoma presenting as obstructive jaundice // Korean J. Gastroenterology 2013; 61 (1): 50-53;
  3. Гальперин Э. И. Стриктуры желчных протоков. В книге: Гальперин Э. И., Дюжева Т. Г. // Лекции по панкреатобилиарной хирургии под редакцией Э. И. Гальперина и Т. Г. Дюжевой. Москва: Видар - М; 2011;
  4. Moreno Luna L. E., Kipp В., Halling К. С. et al. Аdvanced cytologic techniques for the detection of malignant pancreatobiliary strictures // Gastroenterol. 2006; 131(4): 1064-1072;
  5. Taylor A. C., Liile A. F., Hennessy O. H. et al. Prospective blinded study of MRCP compared to ERCP and assessment of their respective clinical roles // Gastroenterol. 2000; 118: A 207;
  6. Parsi M. A. Peroral cholangioscopy-assisted guidewire placement for removal of impacted stones in the cystic duct remnant // W. J. Gastroenterol. 2009; 1(1): 59-61;
  7. Costamagna G., Tringali A., Mutignani M., et al. Endoscopic sphincterotomy for common bile duct stones: long-term follow-up and risk analysis for recurrence // Gastrointest. Endosc. 2000; 51: AB 189;
  8. Weber A., Schmid R. M., Prinz Ch. Diagnostic approaches for cholangiocarcinoma // W. J. Gastroenterol. 2008; 14(26): 4131-4136;
  9. Sharma M. P., Ahuja V. Aetiological spectrum of obstructive jaundice and diagnostic ability of ultrasonography: a clinician’s perspective // Trop. Gastroenterol. 1999; 20: 167-169;
  10. Гальперин Э. И. Стриктуры желчных протоков. В книге: Гальперин Э. И., Дюжева Т. Г. // Лекции по панкреатобилиарной хирургии под редакцией Э. И. Гальперина и Т. Г. Дюжевой. Москва: Видар - М; 2011;
  11. In Hye Cha, Jin Nam Kim, You Sun Kim et al. Metastatic Common Bile Duct Cancer from Pulmonary Adenocarcinoma Presenting as Obstructive Jaundice// Korean Journal of Gastroenterology. - 2013. - Vol. 61 No. 1, 50-53;
  12. Rösch T., Meining A., Frühmorgen S. et al. A prospective comparison of the diagnostic accuracy of ERCP, MRCP, CT, and EUS in biliary strictures // Gastrointest. Endosc. 2002; 55(7): 870-6;
  13. Яшина Н. И., Кармазановский Г. Г. Сложности диагностики рака головки поджелудочной железы при компьютерно-томографическом исследовании: Тез. Докл. XXXIX сессия ЦНИИГ. - Москва, 2013. - 168с.;
  14. Dumot J. A. ERCP: current uses and less-invasive options // Cleve Clin. J. Med. 2006; 73(5): 418-425;
  15. Ширяев С. В., Долгушин Б. И., Хмелев А. В. Современное состояние ПЭТ диагностики в онкологии: Доклад в рамках Заседания Московского Онкологического Общества; тема Позитронная эмиссионная томография. - Москва: 2009;
  16. Anderson C. D., Rice M. H., Pinson C. W., et al. Fluorodeoxyglucose PET imaging in the evaluation of gallbladder carcinoma and cholangiocarcinoma // J. Gastrointest. Surg. 2004; 8: 90-97;
  17. Reinhardt M. J., Strunk H., Gerhardt T., et al. Detection of Klatskin’s tumor in extrahepatic bile duct strictures using delayed 18F-FDG PET/CT: preliminary results for 22 patient studies // J. of Nucl. Med. 2005; 46: 1158-1163;
  18. Itoi T., Osanay M., Igarashi Y. et al. Diagnostic peroral video cholangioscopy is an accurate diagnostic tool for patients with bile duct lesions // Clin. Gastroenterol. Hepatol. 2010; 8(11): 934-8;
  19. Tischendorf J. J., Krüger M., Trautwein C. et al. Cholangioscopic characterization of dominant bile duct stenoses in patients with primary sclerosing cholangitis // Endosc. 2006; 38(7): 665-9;
  20. Da Silveira E. B., Barkun A. N., Romagnuolo J. et al. An economic evaluation from randomizae trial data comparing ERCP to MRCP in suspected biliary obstruction // Gastrointest. Endosc. 2007; 65: AB 95.

Full text is published :
Fomicheva N.V., Shuleshova A.G., Ulyanov D.N. DIAGNOSIS AND TREATMENT OF THE SYNDROME OF OBSTRUCTIVE JAUNDICE. Experimental and Clinical Gastroenterology Journal. 2017;140(04):27-33
Read & Download full text

1. Clinical hospital № 122 named after L. G. Sokolov (Moscow, Russian Federation)
2. Saint Petersburg state University (St. Petersburg, Russian Federation)
3. National medical surgical center n. a.. N. I. Pirogov (Moscow, Russian Federation)

Keywords:bile ducts stricture,ERCP,brush-biopsy,biopsy,EUS,fine needle aspiration,FNA,histology,cholangiocarcinoma,bile ducts cancer,choledoch,common bile duct

Abstract:An analysis of published data on the effectiveness of various methods of diagnosis of obstructive jaundice syndrome, caused by stones and bile duct strictures of various origins. We conducted an analysis of own data on the effectiveness and accuracy cholangioscopy and confocal laser confocal laser endomicroscopy (CLE) in the diagnosis of the causes of biliary obstruction. The efficacy of endoscopic retrograde cholangiopancreatography is considered in combination with additional methods of examination

• References total 52 ⇓ :: .
  1. Khan S. A., Thomas H. C., Davidson B. R., Taylor-Robinson S. D. Cholangiocarcinoma. Lancet, 2005, vol. 367, no. 9523, pp. 1303-1314.
  2. Razumilava N, Gores G. J. Cholangiocarcinoma. Lancet, 2014, vol. 383, no. 9935, pp. 2168-2179.
  3. Mosconi S et al. Cholangiocarcinoma. Crit Rev Oncol Hematol, 2009, vol. 69, no. 3, pp. 259-270.
  4. Lazaridis K. N., LaRusso N. F. The Cholangiopathies. Mayo Clin Proc, 2015, vol. 90, no. 6, pp. 791-800.
  5. Nanda A., Brown J. M., Berger S. H. et al. Triple modality testing by endoscopic retrograde cholangiopancreatography for the diagnosis of cholangiocarcinoma. Therap Adv Gastroenterol, 2015, vol. 8, no. 2, pp. 56-65.
  6. Sethi R., Singh K., Warner B. et al. The impact of brush cytology from endoscopic retrograde cholangiopancreatography (ERCP) on patient management at a UK teaching hospital. Frontline Gastroenterol, 2016, vol. 7, pp. 97-101.
  7. Kim J. Y., Choi J. H., Kim J. H. et al. Clinical usefulness of bile cytology obtained from biliary drainage tube for diagnosing cholangiocarcinoma. Korean J Gastroenterol, 2014, vol. 63, no. 2, pp. 107-13.
  8. Yagioka H., Hirano K., Isayama H. et al. Clinical significance of bile cytology via an endoscopic nasobiliary drainage tube for pathological diagnosis of malignant biliary strictures. J Hepatobiliary Pancreat Sci, 2011, vol. 18, no. 2, pp. 211-215.
  9. Nilsson B., Wee A., Yap I. Bile cytology. Diagnostic role in the management of biliary obstruction. Acta Cytol, 1995, vol. 39, no. 4, pp. 746-752.
  10. Noda Y., Fujita N., Kobayashi G. et al. Prospective randomized controlled study comparing cell block method and conventional smear method for bile cytology. Dig Endosc, 2013, vol. 25, no. 4, pp. 444-452.
  11. Mohandas K. M., Swaroop V. S., Gullar S. U. et al. Diagnosis of malignant obstructive jaundice by bile cytology: results improved by dilating the bile duct strictures. Gastrointest Endosc, 1994, vol. 40, no.2, pp. 150-154.
  12. Fior-Gozlan M., Bosio C., Croset C., Bichard P. Value of bile cytology associated with brush cytology of the bile duct: a comparative study of 115 patients. Ann Pathol, 2006, vol. 26, no. 5, pp. 361-367.
  13. Mahmoudi N., Enns R., Amar J. et al. Biliary brush cytology: Factors associated with positive yields on biliary brush cytology. World J Gastroenterol, 2008, vol. 14, no. 4, pp. 569-573.
  14. Eiholm S., Thielsen P., Kromann-Andersen H. Endoscopic brush cytology from the biliary duct system is still valuable. Dan Med J, 2013, vol. 60, no. 7, pp. A4656.
  15. Schoefl R., Haefner M., Wrba F. et al. Forceps biopsy and brush cytology during endoscopic retrograde cholangiopancreatography for the diagnosis of biliary stenoses. Scand J Gastroenterol, 1997, vol. 32, no. 4, pp. 363-368.
  16. Harewood G. C., Baron T. H., Stadheim L. M. et al. Prospective, blinded assessment of factors influencing the accuracy of biliary cytology interpretation. Am J Gastroenterol, 2004, vol. 99, no. 8, pp. 1464-1469.
  17. de Bellis M., Fogel E. L., Sherman S. et al. Influence of stricture dilation and repeat brushing on the cancer detection rate of brush cytology in the evaluation of malignant biliary obstruction. Gastrointest Endosc, 2003, vol. 58, no. 2, pp. 176-182.
  18. Roth G. S., Bichard P., Fior-Gozlan M. et al. Performance of bile aspiration plus brushing to diagnose malignant biliary strictures during endoscopic retrograde cholangiopancreatography. Endosc Int Open, 2016, vol. 4, no.9, pp. E 997-E 1003.
  19. Fogel E. L., deBellis M., McHenry L. et al. Effectiveness of a new long cytology brush in the evaluation of malignant biliary obstruction: a prospective study. Gastrointest Endosc, 2006, vol. 63, no. 1, pp. 71-77.
  20. Mehmood S., Loya A., Yusuf M. A. Biliary Brush Cytology Revisited. Acta Cytol, 2016, vol. 60, no. 2, pp. 167-172.
  21. Weber A., von Weyhern C., Fend F. et al. Endoscopic transpapillary brush cytology and forceps biopsy in patients with hilar cholangiocarcinoma. World J Gastroenterol, 2008, vol. 14, no. 7, pp. 1097-1101.
  22. Bang K. B., Kim H. J., Park J. H. et al. Comparison of brush and basket cytology in differential diagnosis of bile duct stricture at endoscopic retrograde cholangiopancreatography. Hepatobiliary Pancreat Dis Int, 2014, vol. 13, no. 6, pp. 622-627.
  23. Varadarajulu S., Bang J. Y., Hasan M. K. et al. Improving the diagnostic yield of single-operator cholangioscopy-guided biopsy of indeterminate biliary strictures: ROSE to the rescue? (with video). Gastrointest Endosc, 2016, vol. 84, no. 4, pp. 681-687.
  24. Heinzow H. S., Woestmeyer C., Domschke W. et al. Endoscopic transpapillary biopsies are of limited value in the diagnostics of bile duct strictures of unknown etiology-results of a histopathologically controlled study in 312 patients. Hepatogastroenterology, 2013, vol. 60, no. 127, pp. 1569-1572.
  25. Chen W. M., Wei K. L., Chen Y. S. et al. Transpapillary biliary biopsy for malignant biliary strictures: comparison between cholangiocarcinoma and pancreatic cancer. World J Surg Oncol, 2016, vol. 14, p. 140.
  26. Domagk D., Poremba C., Dietl K. H. et al. Endoscopic transpapillary biopsies and intraductal ultrasonography in the diagnostics of bile duct strictures: a prospective study. Gut, 2002, vol. 51, no. 2, pp. 240-244.
  27. Weber A., Schmid R. M., Prinz C. Diagnostic approaches for cholangiocarcinoma. World J Gastroenterol, 2008, vol. 14, no. 26, pp. 4131-4136.
  28. Ierardi A. M., Mangini M., Fontana F. et al. Usefulness and safety of biliary percutaneous transluminal forceps biopsy (PTFB): our experience. Minim Invasive Ther Allied Technol, 2014, vol. 23, no. 2, pp. 96-101.
  29. Tamada K., Kurihara K., Tomiyama T. et al. How many biopsies should be performed during percutaneous transhepatic cholangioscopy to diagnose biliary tract cancer? Gastrointest Endosc, 1999, vol. 50, no. 5, pp. 653-658.
  30. Shah R. J., Langer D. A., Antillon M. R., Chen Y. K. Cholangioscopy and cholangioscopic forceps biopsy in patients with indeterminate pancreaticobiliary pathology. Clin Gastroenterol Hepatol, 2006, vol.4, pp. 219-225.
  31. Kim H. J., Kim M. H., Lee S. K. et al. Tumor vessel: a valuable cholangioscopic clue of malignant biliary stricture. Gastrointest Endosc, 2000, vol. 52, no.5, pp. 635-638.
  32. Fukuda Y., Tsuyuguchi T., Sakai Y. et al. Diagnostic utility of peroral cholangioscopy for various bile-duct lesions. Gastrointest Endosc, 2005, vol. 62, no. 3, pp. 374-382.
  33. Itoi T., Osanai M., Igarashi Y. et al. Diagnostic peroral video cholangioscopy is an accurate diagnostic tool for patients with bile duct lesions. Clin Gastroenterol Hepatol, 2010, vol. 8, no. 11, pp. 934-938.
  34. Yang J. F., Sharaiha R. Z., Francis G. et al. Diagnostic accuracy of directed cholangioscopic biopsies and confocal laser endomicroscopy in cytology-negative indeterminate bile duct stricture: a multicenter comparison trial. Minerva Gastroenterol Dietol, 2016, vol. 62, no. 3, pp. 227-233.
  35. Chen Y. K., Pleskow D. K. SpyGlass single-operator peroral cholangiopancreatoscopy system for the diagnosis and therapy of bile-duct disorders: a clinical feasibility study (with video). Gastrointest Endosc, 2007, vol. 65, no. 6, pp. 832-841.
  36. Manta R., Frazzoni M., Conigliaro R. et al. SpyGlass single-operator peroral cholangioscopy in the evaluation of indeterminate biliary lesions: a single-center, prospective, cohort study. Surg Endosc, 2013, vol. 27, no. 5, pp. 1569-1572.
  37. Siddiqui A. A., Mehendiratta V., Jackson W. et al. Identification of cholangiocarcinoma by using the Spyglass Spyscope system for peroral cholangioscopy and biopsy collection. Clin Gastroenterol Hepatol, 2012, vol. 10, no. 5, pp. 466-471.
  38. Weilert F., Bhat Y. M., Binmoeller K. F. et al. EUS-FNA is superior to ERCP-based tissue sampling in suspected malignant biliary obstruction: results of a prospective, single-blind, comparative study. Gastrointest Endosc, 2014, vol. 80, no. 1, pp. 97-104.
  39. Nguyen K., Sing J. T. Jr. Review of endoscopic techniques in the diagnosis and management of cholangiocarcinoma. World J Gastroenterol, 2008, vol. 14, no. 19, pp. 2995-2999.
  40. Garrow D., Miller S., Sinha D. et al. Endoscopic ultrasound: a meta-analysis of test performance in suspected biliary obstruction. Clin Gastroenterol Hepatol, 2007, vol. 5, pp. 616-623.
  41. Nayar M. K., Manas D. M., Wadehra V., Oppong K. E. Role of EUS/EUS-guided FNA in the management of proximal biliary strictures. Hepatogastroenterology, 2011, vol. 58, pp. 1862-1865.
  42. Fritscher-Ravens A., Broering D. C., Knoefel W. T. et al. EUS-guided fine-needle aspiration of suspected hilar cholangiocarcinoma in potentially operable patients with negative brush cytology. Am J Gastroenterol, 2004, vol. 99, pp. 45-51.
  43. Eloubeidi M. A., Chen V. K., Jhala N. C. et al. Endoscopic ultrasound-guided fine needle aspiration biopsy of suspected cholangiocarcinoma. Clin Gastroenterol Hepatol, 2004, vol. 2, pp. 209-213.
  44. Tummala P., Munigala S., Eloubeidi M. A., Agarwal B. Patients with obstructive jaundice and biliary stricture ± mass lesion on imaging: prevalence of malignancy and potential role of EUS-FNA. J Clin Gastroenterol, 2013, vol. 47, pp. 532-537.
  45. Mohamadnejad M., Dewitt J. M., Sherman S. et al. Role of EUS for preoperative evaluation of cholangiocarcinoma: a large single-center experience. Gastrointest Endosc, 2011, vol. 73, pp. 71-78.
  46. Fletcher N. D., Wise P. E., Sharp K. W. Common bile duct papillary adenoma causing obstructive jaundice: case report and review of the literature. Am Surg, 2004, vol. 70, pp. 448-452.
  47. Penn I. Primary malignancies of the hepato-biliary-pancreatic system in organ allograft recipients. J Hepatobiliary Pancreat Surg, 1998, vol. 5, pp. 157-164.
  48. Gleeson F. C., Rajan E., Levy M. J. et al. EUS-guided FNA of regional lymph nodes in patients with unresectable hilar cholangiocarcinoma. Gastrointest Endosc, 2008, vol. 67, pp. 438-443.
  49. Pollack M. J., Gholam P. M., Chak A. EUS-FNA in unresectable cholangiocarcinoma: a novel indication. Gastrointest Endosc, 2008, vol. 67, pp. 444-445.
  50. El Chafic A. H., Dewitt J., Leblanc J. K. et al. Impact of preoperative endoscopic ultrasound-guided fine needle aspiration on postoperative recurrence and survival in cholangiocarcinoma patients. Endoscopy, 2013, vol. 45, pp. 883-889.
  51. Dumonceau J. M., Koessler T., van Hooft J. E., Fockens P. Endoscopic ultrasonography-guided fine needle aspiration: Relatively low sensitivity in the endosonographer population. World J Gastroenterol, 2012, vol. 18, no. 19, pp. 2357-2363.
  52. Curcio G., Traina M., Mocciaro F. et al. Intraductal aspiration: a promising new tissue-sampling technique for the diagnosis of suspected malignant biliary strictures. Gastrointest Endosc, 2012, vol. 75, no. 4, pp. 798-804.

Full text is published :
Solonitsyn E.G., Titov A.K., Vorobev S.L., Tamazyan N.V. et al. ENDOSCOPIC TECHNIQUES OF OBTAINING MATERIAL FOR MORPHOLOGICAL EXAMINATION FOR BILE DUCTS STRICTURES. Experimental and Clinical Gastroenterology Journal. 2017;140(04):34-40
Read & Download full text

1. Siberian State Medical University (Tomsk, Russian Federation)
2. Siberian Federal Sciene-Clinical Centre FMBA Russian Federation (Tomsk, Russian Federation)

Keywords:chronic cholecystitis,chronic opisthorchiasis,conjugate of clinical signs,the predictors of progression to cholecystitis

Abstract:Using contingency tables and logistic regression in clinical studies reveal the interconnectedness of all qualitative characteristics and predictors of disease progression. The results are natural and suggests that the indicators of liver function and biliary system activity in chronic cholecystitis combined with opisthorchiasis interrelated, interdependent and mutually. The results of complex statistical analysis can determine predictors of disease progression, which should be used for timely treatment and preventive measures aimed at the prevention of disease progression.

• References total 22 ⇓ :: .
  1. Ильченко А. А. Болезни желчного пузыря и желчных путей. М.: Медицинское информационное агентство; 2011, 880с.
  2. Лоранская И. Д. Функциональные расстройства билиарного тракта /Учебное пособие. М.: Форте принт: 2013, 92 с.
  3. Лоранская И. Д., Кукушкин М. Л., Панина Н. А. Билиарные дисфункции и их профилактика //Экспериментальная и клиническая гастроэнтерология. 2011; № 5: 48-52.
  4. Пальцев А. И., Дарянина С. А. Фитотерапия хронического описторхоза. Новосибирск: Изд-во СО РАН: 2004, 140 с.
  5. Полунина Т. Е. Алгоритм диагностики и лечения дисфункций билиарного тракта //Архивь внутренней медицины. 2015; № 1(21): 27-32.
  6. Минушкин О. Н. Сочетанные функциональные расстройства ЖКТ. Их диагностика и лечебные подходы // Медицинский совет. 2015; № 13: 20-25.
  7. Ардатская М. Д. Функциональные расстройства билиарного тракта: проблемы диагностики и лечения // Фарматека. 2012; № 2: 71-77.
  8. Плотникова Е. Ю., Александрова А. Ю., Белобородова Э. И. и др. Биохимические особенности состава пузырной желчи при патологии желчевыводящих путей //Клиническая лабораторная диагностика: научно-практический журнал. 2007; № 6: 33-36.
  9. Тюрюмин Я. Л. В Шантуров.А., Тюрюмина Е. Э. Патогенез и лечение холестеринового холецистолитиаза (обзор) //Бюллетень ВСНЦ СО РАМН. 2012; № 2 (84), Часть 2: 181-186.
  10. Кнышова В. В., Веремчук Л. В., Шейкина А. И. Взаимосвязь метаболических нарушений и функционального состояния печени при хроническом некалькулезном холецистите //Вестник новых медицинских технологий. 2011; Т.XVIII, № 3: 3-39.
  11. Абаев Ю. К. Клинические испытания в доказательной медицине //Медицинские новости. 2008; № 10: 7-14.
  12. Поддубная О. А. Сопряженность особенностей проведения комплексной физиотерапии с ее эффективностью у больных хроническим холециститом //Физиотерапия, бальнеология и реабилитация. 2014; № 6: 19-24.
  13. Пронин C. B., Егорова Л. С., Чухрова М. Г. и др. Соматоформные расстройства у пациентов с хроническим некалькулезным холециститом //Мир науки, культуры, образования. 2013; № 3 (40): 388-391.
  14. Камзеев Д. В. Прогностическое значение факторов риска церебрального инсульта у больных с функциональными, дегенеративно-дистрофическими нарушениями шейного отдела позвоночника и начальными проявлениями недостаточности кровоснабжения мозга //Автореф. Дис… канд. мед. наук. Казань. 2007, 32с.
  15. Истомина Н. Г. Предикторы эктопической беременности: исследование типа случай-контроль //Акушерство и гинекология. 2008; № 2: 31-34.
  16. Финк Г. Ф. Предикторы социальной адаптации при шизотипическом расстройстве //Вестник Смоленской медицинской академии. 2000; Вып.3: 115-116.
  17. Beaugerie L., Seksik P., Nion-Larmurier I. et al. Predictors of Crohn’s Disease //Gastroenterology. March 2006;130:650-656.
  18. Крупицкий Е. М., Борцов А. В. Парадигма доказательной медицины: принципы проведения клинических исследований //Журнал неврологии и психиатрии им. С. С. Корсакова. 2008; № 2: 9-12.
  19. Кендалл М., Стьюарт А. Статистические выводы и связи. Пер. с англ. М.: Главная редакция физ.-мат. литературы. 1973, 899 с.
  20. Леонов В. П. Обработка экспериментальных данных на программируемых микрокалькуляторах. Томск, изд-во ТГУ. 1990, 376с.
  21. David W. Hosmer. Jr., Stanley Lemeshow. Applied logistic regression- 2nd ed. John Wiley & Sons, Inc. 2000, 397 pp.
  22. McDowell S.E., Coleman J.J, Ferner R. E. Systematic review and meta-analysis of ethnic differences in risks of adverse reactions to drugs used in cardiovascular medicine. BMJ. May 20, 2006;332;1177-1181.

Full text is published :
Poddubnaya O.A. ANALYSIS OF CONTINGENCY FUNCTIONAL ACTIVITY OF HEPATOBILIARY SYSTEM IN CHRONIC CHOLECYSTITIS. Experimental and Clinical Gastroenterology Journal. 2017;140(04):41-47
Read & Download full text

1. Medical center “Yerevan” (Yerevan, Armenia)
2. Yerevan state medical University. M. Heratsi; Medical center “Nairi” (Yerevan, Armenia)

Keywords:calculous cholecystitis,high operative-anesthesiological risk,ultrasound,magnetic resonance imaging

Abstract:The article discusses current possibilities of visualization of the biliary tract in persons with calculous cholecystitis of the group’s high operational and anesthetic risk. According to the results of the comparative analysis of the main characteristics of such diagnostic methods as ultrasound, MRI and RPH the authors come to the conclusion about the benefits of magnetic resonance imaging. This method showed the greatest sensitivity and accuracy in detecting calculous cholecystitis patients with high operative-anesthesiological risk.

• References total 6 ⇓ :: .
  1. Никитин А. Д. Место ультразвукового исследования в диагностике заболеваний желчного пузыря // Бюллетень медицинских Интернет-конференций. - 2013. - Т. 3, № 2. - С. 204
  2. Ратников В. А., Черемисин В. М., Шейко С. Б. Современные лучевые методы (ультразвуковое исследование, рентгеновская компьютерная и магнитно-резонансная томография) в диагностике холедохолитиаза (обзор литературы) // Медицинская визуализация. - 2002. - № 3. - С. 99-106
  3. Рогожникова А. В., Климашин Д. Ф., Клименко Г. А. Информативность магнитно-резонансной томографии (МРТ) диагностики при выявлении заболеваний панкреато-билиарной зоны // Бюллетень медицинских Интернет-конференций. - 2013. - Т. 3, № 3. - С. 789
  4. Скирда И. Ю., Гладун В. М., Закревская О. В. Точность методов визуализации в диагностике острого холецистита // Гастроэнтерология. - 2015. - № 1 (55). - С. 31-41
  5. Тарасенко Л. А., Литвиненко И. В., Мандриченко А. С., Ерков А. А. Ультразвуковое исследование в диагностике остро калькулезного холецистита // Медицинская наука и образование Урала. - 2008. - № 1. - С. 34-36
  6. Imaging in Hepatobiliary and Pancreatic Disease. A Practical Clinical Approach / Ed. by van Leeuwen D. J., Reeders J. W.A.I., Ariyama J. Harcourt Publishers Limited, 2000. 525 p.

Full text is published :
Balayan G.Z., Gomtsyan N.A., Gomtsyan N.A., Ghalumyan K.S. et al. THE EFFECTIVENESS OF DIFFERENT IMAGING MODALITIES IN THE DIAGNOSIS OF CALCULOUS CHOLECYSTITIS IN PATIENTS WITH HIGH OPERATIVE-ANESTHESIOLOGICAL RISK. Experimental and Clinical Gastroenterology Journal. 2017;140(04):48-51
Read & Download full text

1. Kyrgyz-Russian Slavic University named after B. N. Yeltsin (Bishkek, Kyrgyzstan)

Keywords:single-voxel proton spektoroskopiya,focal lesions of the liver

Abstract:Purpose of the study - to assess the effectiveness of the diagnostic use of proton spectroscopy in focal lesions of the liver parenchyma. Material and methods: A 160 of the abdominal cavity of patients with focal lesions of the liver (36 patients - liver cancer (including cases of cholangiocarcinoma and cirrhosis, cancer); 28 patients - with single and multiple metastases in the liver parenchyma; 45 observation of single and multiple hemangiomas of the liver, 31 cases of infiltrative and cystic forms alveokokkovogo infiltrative lesion, 20 patients with liver parenchyma unchanged in the control group). The scanning protocol that included MR proton spectroscopy. The studies were conducted on the unit Philips Infinion 1,5T. In the spectrograms of proton spectra and tables were evaluated: height of the peaks; peak area; creatinine ratio of peak area to other metabolites; creatinine ratio of peak area to other metabolites; percentage of metabolites in the spectrum, represented as a relative value. Conclusion: The single-voxel proton spektoroskopiya has the potential to be used as differential diagnostic criteria of focal hepatic lesions.

• References total 8 ⇓ :: .
  1. Труфанов Г. Е., Тютин Л. А. Магнитно-резонансная спектроскопия. Санкт-Петербург: «Элби-Спб», 2008, 337 с.
  2. Лундин А.Г, Федин Э. И. ЯМР спектроскопия. М: Наука. 1986; 223 с.
  3. Подопригора А. Е., Пронин И. Н., Фадеева Л. М. Протонная магнитно резонансная спектроскопия в диагностике опухолевых и неопухолевых поражений головного мозга // Мед. виз. 2000. № 4. С. 86-92.
  4. Simmons M. L., Frodonza C. G. and Coyle J. T. Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies. Neuroscience. 1991; 45: 37745.
  5. Семенова Н. А. Метод ЯМР спектроскопии в прижизненных исследованиях обменных процессов. Особенности энергетического метаболизма головного мозга по данным ЯМР in vivo. Успехи современной биологии РАН. 2005; 125: 419-430.
  6. Bulakbasia N., Kocaoglua M., Цrsa F. et al. Combination of Single Voxel Proton MR Spectroscopy and Apparent Diffusion Coefficient Calculation in the Evaluation of Common Brain Tumors // Am. J. Neuroradiol. 2003. V.24. P. 225-233.
  7. Семенова Н. А., Ахадов Т. Ф., Ситников С. Л., Варфоломеев С. Д. Перспективы магнитно-резонансной спектроскопии как метода диагностики в невропатологии // Медицинская визуализация, № 2, 2009, с 73-81.
  8. Ложкин С. Н., Тиканадзе А. Д. Тюрюмина М. И. Глутамин и его роль в интенсивной терапии. Вестник интенсивной терапии, - 2003 № 4. Клиническое питание.

Full text is published :
Bebezov B.H., Bogdanov A.V., Sabirov I.S., Sabirov I.S. THE POSSIBILITY OF USING THE PROTON SPECTROSCOPY AT FOCAL LESIONS OF THE LIVER PARENCHYMA. Experimental and Clinical Gastroenterology Journal. 2017;140(04):52-57
Read & Download full text

1. FGBOU SPE Russian Medical Academy of Postgraduate Education (Moscow, Russian Federation)

Keywords:chronic abdominal syndrome,erosions and ulcers of the stomach and duodenum

Abstract:Aim of study was determination of especially clinic and diagnostic erosive and ulcerative lesions of gastroduodenal zone in patients with abdominal angina. Materials and Methods. Results of diagnostic and treatment 96 patients with abdominal angina. Results. Upper gastrointestinal endoscopy revealed erosive lesions in 44 cases, the bulb ulcers - in 3 cases, diffuse atrophy of the mucous - in 43 cases, focal gastropathy - in 53 cases.

• References total 35 ⇓ :: .
  1. Губергриц Н. Б., Агапова Н. Г. Абдоминальный ишемический синдром // Doktor. - 2004. - № 3. - С. 7-11.
  2. Калинин А. В., Степуро Д. К., Корнеев Н. В. и др. Хронический абдоминальный ишемический синдром и сочетанные с ним заболевания: особенности клиники, диагностики и лечения// Клинические перспективы гастроэнтерологии, гепатологии. - 2003. № 6С.19-23.
  3. Звенигородская Л. А., Н. Г. Самсонова, Топорков А. С. Хроническая ишемическая болезнь органов пищеварения: алгоритм диагностики и лечения // Фарматека. - 2010. - № 2. - С. 78-82.
  4. Логинов A. C., Звенигородская Л. А. Хроническая абдоминальная ишемия // Терапевт, арх, 2000. - J&2. - С. 36-40.
  5. Покровский А. В., Казанчян П. О., Гринберг А. А. и др. Функционально-морфологическое состояние желудочно-кишечного тракта в условиях хронических циркуляторных расстройств// Тер. арх. - 1983. - № 2. - С. 93-6.
  6. Клиническая ангиология /Под ред. академика РАМН А. В. Покровского. - Т. 2. - М.: Медицина, 2004. - 887 с.
  7. Луканов В. В., Фомина И. Г., Георгадзе З. О. и др. Трудности диагностики острых сосудистых заболеваний брюшной полости// Клин. мед. - 2005. - № 5. - С. 61-65.
  8. Ойноткинова О. Ш., Немытин Ю. В. Атеросклероз и абдоминальная ишемическая болезнь // М.: Медицина, 2001. - 312 с.
  9. Сохач А. Я. Причины возникновения и основные патогенетические механизмы развития атеросклеротической абдоминальной ишемической болезни// Медицинский вестник Северного Кавказа. - 2007. - № 4. - С. 3-8.
  10. Яковлев В. М., Хайт Г. Я., Сохач А. Я. Атеросклеротичекая абдоминальная ишемическая болезнь (патогенез, клиника, диагностика)//М.: «УИЦ XXI век», 2009. - 166.
  11. Plonka A. J. Atherosclerotic narrowings of themesenteric circulation/AJ Plonka, T. Tolloczko, M. Lipski et al. // Vac Surg. - 1989. - Vol. 92. - P. 202-5.
  12. Игнашов А. М., Канаев А. И., Курков А. А., Перлей В. Е., Новикова А. С. Компрессионный стеноз чревного ствола у детей и подростков (клиника, диагностика и хирургическое лечение) // Вестник хирургии. 2004. № 5. С. 78-81.
  13. Игнашов А. М., Тюрина Т. В., Перлей В. Е. и др. Хроническая рецидивирующая боль в животе и нейровегетативные расстройства у детей и подростков при синдроме компрессии чревного ствола // Амбулаторная хирургия. 2006. № 1 (21). С. 18-21.
  14. Вовк А. В., Шугаев А. И., Бабкин В. Я. Острые нарушения мезентериального кровообращения в неотложной хирургии органов брюшной полости// Вестн. хир. - 2006. - № 6. - С. 87-88.
  15. Гавриленко А. В., Косенков А. Н. Диагностика и хирургическое лечение хронической абдоминальной ишемии. М.: Медицина. 2000. - 169 с.
  16. Петровский Б. В., Гавриленко А. В. Хроническая абдоминальная ишемия: 35-летний опыт хирургического лечения // Анналы хирургии. - 2003. - № 3. - С. 10-14.
  17. Соколович Л. Г. Сосудистая хирургия и ангиология // Д: Феникс; Красноярск: Издательские проекты, 2006. - 176с.
  18. Libicher M., Reichert V., Fleksic M. et al. Balloon Occlusion of the Celiac Artery: A Test for Evaluation of Collateral Circulation Prior Endovascular Coverage // European Journal of Vascular and Endovascular Surgery. - 2008. - V. 36, № 3. - P. 303-305.
  19. Carr S. C., Mahvi D. M., Hoch J. R. et al. Visceral artery aneurysm rupture //J. Vasc. Surg. - 2001. - V. 33, № 4. - P. 806-811.
  20. Bacelli G. Aneurisma dell\’arteria mesenterica superiore/G. Bacelli//Policlinico Soz Med. - 1914. - N 11. - P. 301-3.
  21. Mitchell E. L., Chang E. Y., Landry G. J. et al. Duplex criteria for native superior mesenteric artery stenosis overestimate stenosis in stented superior mesenteric arteries // J. Vase. Surg. 2009; 50(2): 335-40.
  22. Аруин Л. И., Капуллер Л. Л., Исаков В. А. Морфологическая диагностика болезней желудка и кишечника. М.: Триада-Х. 1998. 483 с.
  23. Канаев А. И., Игнашов А. М. Клиника, диагностика, лечение синдрома компрессии чревного ствола //Вестник Санкт-Петербургской государственной медицинской академии им. акад. И. И. Мечникова. 2006. № 3. С. 125-129.
  24. Острая интестинальная ишемия: диагностика и хирургическое лечение / А. А. Баешко, В. В. Климович, В. А. Юшкевич и др. // Новые технологии в медицине: диагностика, лечение, реабилитация. - 2002. - С. 48-50.
  25. Комиссаров И. А., Игнашов А. М., Комаров К. М. Хронические боли в животе у детей. Возможные причины и лечение // Детская хирургия. 2006. № 3. С. 19-23.
  26. Шульпекова Ю. О., Драшганя О. М., Ивашкин В. Т. Абдоминальный болевой синдром//Рос. журнал гастроэнтерологин, гепатологии, колопроктологии. - 2002. С. 8-15.
  27. Ischemic gastropathy Jeopard sjcin in the stomach / T.C, Lee et al. // Endoscopy - 2005 - Vol, 37, N 9 - P 927.
  28. Kolkman J. J., Bargeman M., Huisman A. B., Geelkerken R. H. Diagnosis and management of splanchnic ischemia // World J. Gastroenterol. - 2008 Dec 28. - 14(48). - 7309-20.
  29. Mensink P. B., Moons L. M., Kuipers E. J. Chronic gastrointestinal ischaemia: shifting paradigms // Gut. - 2010 Nov 29. - P. 112-118.
  30. Лазебник Л. Б., Звенигородская Л. А. Хроническая ишемическая болезнь органов пищеварения. - 2003. - 136 с.
  31. Поташов Л. В., Князев М. В., Игнашов А. М. Ишемическая болезнь органов пищеварения. Л.: Медицина. 1985. 216 с.
  32. Савельев В. С. Петухов В. А., Бычков С. Г. и др. Нарушения микроциркуляции при хронической ишемической болезни органов пищеварения и дислипопротеидемии // Грудная и сердечно-сосуд. хирургия. - 1999. - No 4. - С. 40-45.
  33. Кохан Е. П., Белякин С. А., Иванов В.А и др. Диагностика и хирургические методы лечения больных хронической абдоминальной ишемией // Ангиология и сосудистая хирургия. - 2010. - № 4. - С. 135-138.
  34. Щербюк А. Н., Кондрашин С. А., Зайцев А. Ю. Малоинвазивные технологии в диагностике и лечении заболеваний магистральных артерий// Хирургия. - 2005. - № 3. - С. 10-17.
  35. Kruger A. J., Walker P. J., Foster W. J. et al. Open surgery for atherosclerotic chronic mesenteric ischemia//J Vase Surg. - 2007. - Vol. 46(5). - P. 941-945.

Full text is published :
Chernekhovskaya N.E., Povalyaev A.V., Oynotkinova O.Sh., Andreev V.G. et al. EROSIVE AND ULCERATIVE LESIONS OF GASTRODUODENAL ZONE IN PATIENTS WITH ABDOMINAL ANGINA. Experimental and Clinical Gastroenterology Journal. 2017;140(04):58-63
Read & Download full text

1. Moscow Cancer Research Institute (Moscow, Russian Federation)

Keywords:chronic abdominal syndrome,erosions and ulcers of the stomach and duodenum

Abstract:Majority of published data describing endocytoscopic examination of upper gastrointestinal tract mucosa, but in recent publications, it is reported, that endocytoscopy is suitable for small bowel, colon, respiratory tract and even peritoneum «optical biopsy». In number of articles possibilities of celiac sprue diagnostics with endocytoscopy is dicscussed, but small-bowel endocytoscopy is limited, due to absence of endocytoscopes, compatible with enteroscopes. More widely endocytoscopy is used in colon, mostly in lateral-spreading adenomas diagnostics. Prof. S-E. Kudo developed endocytoscopic classification of colonic mucosa changes, used for differential diagnostics and lesion mapping, describing hyperplasia, adenomas with different grades of intraepithelial neoplasia, non-invasive and invasive cancer. Some authors reported about good possibilities of endocytoscopy in inflammatory bowel disease diagnostics. Most of data, related to respiratory tract endocytoscopic examination, focused on precancerous conditions and early pharyngeal and lung cancer, and the preliminary results are promising, but, unfortunately, for now, endocytoscopy in bronchial tree is limited, due to lack of thin endocytoscopes. According to some article data, it is possible to use endocytoscopy not only in gastrointestinal and respiratory tract, but also in optical confirmation of peritoneal tumor dissemination in gastric and ovarian cancer patients, and - in bladder mucosa examination.

• References total 34 ⇓ :: .
  1. Inoue H, Kudo SE, Shiokawa A. (2005) in Vivo Imaging of Living Cancer Cell and Evaluation for Tissue Atypia Using Endocytoscopy: ECA (Endocytoscopic Atypia) Classification in the Esophagus and Stomach
  2. Clin Gastroenterol Hepatol. Jul;3(7 Suppl 1): S 61-3.
  3. Kudo S, Sasajima K, Inoue H et al. (2007) [Recent progress in endocytoscopy system: Classification of endocytoscopy]. Nihon Naika Gakkai Zasshi.Feb 10;96(2):252-65. Review
  4. Matysiak-Budnik, T., Coron, E., Mosnier, J. F., Le Rhun, M., Inoue, H., & Galmiche, J. P. (2010). In vivo real-time imaging of human duodenal mucosal structures in celiac disease using endocytoscopy. Endoscopy, 42, 191-196. doi:10.1055/s-0029-1243838
  5. West J, Logan RF, Hill PG, et al. (2007) The iceberg of celiac disease: what isbelow the waterline? Clin Gastroenterol Hepatol;5:59-62).,
  6. Pohl, H., Rösch, T., Tanczos, B. T., Rudolph, B., Schlüns, K., & Baumgart, D. C. (2009). Endocytoscopy for the detection of microstructural features in adult patients with celiac sprue: a prospective, blinded endocytoscopy-conventional histology correlation study. Gastrointestinal Endoscopy, 70(5), 933-941. doi:10.1016/j.gie.2009.04.043
  7. Rao, G. V., Mansard, M. J., Rebala, P., Sekaran, A., & Reddy, D. N. (2009). Endocytoscopy assisted laparoscopic intraoperative diagnosis of disseminated malignancy. Surgical Endoscopy and Other Interventional Techniques, 23, 2395-2396. doi:10.1007/s00464-009-0365-y
  8. Watanabe D et al. (2013) Endocytoscopy provides an in vivo virtual histo- pathological diagnosis of Whipple’s disease, 45, 143-144. Endoscopy, 45, 2013, E 143-144
  9. Neumann, H. (2013). Real-time in vivo histologic examination using a probe-based endocytoscopy system for differentiating duodenal polyps, Endoscopy, 45, 53-54.
  10. Shiwaku, H., Kudo, S., Ikehara, N., Ohtsuka, K., Ogata, N., Wakamura, K. (2010). Use of endocytoscopy in the diagnosis of a rare, depressed-type ileal adenoma. Endoscopy, 42, 326-327. doi:10.1055/s-0030-1255890
  11. Fasoli, A., Pugliese, V., Gatteschi, B., Spina, B., Munizzi, F., Frascio, F., … Meroni, E. (2008). Endocytoscopic imaging of a carcinoid tumor. Gastrointestinal Endoscopy, 68(5), 1015-1017. doi:10.1016/j.gie.2008.02.039
  12. Scherübl, H., Jensen, R. T., Cadiot, G., Stölzel, U., & Klöppel, G. (2010). Neuroendocrine tumors of the small bowels are on the rise: Early aspects and management. World Journal of Gastrointestinal Endoscopy, 2(10), 325-334. doi:10.4253/wjge.v2.i10.325
  13. Kwon, R. S., Wong Kee Song, L.-M., Adler, D. G., Conway, J. D., Diehl, D. L., Farraye, F. a, … Tierney, W. M. (2009). Endocytoscopy. Gastrointestinal Endoscopy, 70(4), 610-613. doi:10.1016/j.gie.2009.06.030
  14. Liu HH, Kudo SE, Juch JP. (2005) Pit pattern analysis by magnifying chromoendoscopy for the diagnosis of colorectal polyps. J Formos Med Assoc. 2003 Mar;102(3):178-82.
  15. Hewett DG, Kaltenbach T, Sano Y, Tanaka S, Saunders B, Ponchon T, Soetikno R, Rex DK. (2012) Validation of a Simple Classification System for Endoscopic Diagnosis of Small Colorectal Polyps Using Narrow-Band Imaging. Gastroenterology. May 15).
  16. Sasajima, K., Kudo, S. E., Inoue, H., Takeuchi, T., Kashida, H., Hidaka, E., … Shiokawa, A. (2006). Real-time in vivo virtual histology of colorectal lesions when using the endocytoscopy system. Gastrointestinal Endoscopy, 63(7), 1010-1017. doi:10.1016/j.gie.2006.01.021
  17. Kudo, S. E., Wakamura, K., Ikehara, N., Mori, Y., Inoue, H., & Hamatani, S. (2011). Diagnosis of colorectal lesions with a novel endocytoscopic classification a pilot study. Endoscopy, 43, 869-875. doi:10.1055/s-0030-1256663
  18. Cipolletta, L. (2009). Endocytoscopy can identify dysplasia in aberrant crypt foci of the colorectum: a prospective in vivo study. Endoscopy, 41, 129-132. doi:10.1055/s
  19. Rotondano, G., Bianco, M. A., Salerno, R., Meucci, C., Prisco, A., Garofano, M. L., … Cipolletta, L. (2010). Endocytoscopic classification of preneoplastic lesions in the colorectum. International Journal of Colorectal Disease, 25, 1111-1116. doi:10.1007/s00384-010-0969-7
  20. Mori, Y., Kudo, S., Ikehara, N., Wakamura, K., Wada, Y., Kutsukawa, M., … Hamatani, S. (2013). Comprehensive diagnostic ability of endocytoscopy compared with biopsy for colorectal neoplasms: A prospective randomized noninferiority trial. Endoscopy, 45, 98-105. doi:10.1055/s-0032-1325932
  21. Mori, Y., Kudo, S., Wakamura, K., & Misawa, M. (2014). Novel computer-aided diagnostic system for colorectal lesions by using endocytoscopy (with videos). Gastrointestinal Endoscopy, 1-9. doi:10.1016/j.gie.2014.09.008
  22. Yan, B. (2008). In vivo real-time endocytoscopic visualization of blood flow in rectal microvasculature. Endoscopy, 4, 534-536. doi:10.1055/s
  23. Bessho, R., Kanai, T., Hosoe, N., Kobayashi, T., Takayama, T., Inoue, N., … Hibi, T. (2011). Correlation between endocytoscopy and conventional histopathology in microstructural features of ulcerative colitis. Journal of Gastroenterology, 1-6. doi:10.1007/s00535-011-0439-1
  24. Hosoe, N., Kobayashi, T., Kanai, T., & Bessho, R. (2010). In vivo visualization of trophozoites in patients with amoebic colitis by using a newly developed endocytoscope. YMGE, 72(3), 643-646. doi:10.1016/j.gie.2010.04.031
  25. Shimizu, Y., Takahashi, M., Yoshida, T., Ono, S., Mabe, K., Kato, M., … Sakamoto, N. (2013). Endoscopic in vivo cellular imaging of superficial squamous cell carcinoma of the head and neck by using an integrated endocytoscopy system (with video). Gastrointestinal Endoscopy, 78(2), 351-358. doi:10.1016/j.gie.2013.03.1336
  26. Inoue, H. (2006). Endoscopic in vivo evaluation of tissue atypia in the esophagus using a newly designed integrated endocytoscope: a pilot trial. Endoscopy, 38(January), 891-895. doi:10.1055/s
  27. Shibuya, K., Fujiwara, T., Yasufuku, K., Alaa RM, M., Chiyo, M., Nakajima, T., … Yoshino, I. (2011). In vivo microscopic imaging of the bronchial mucosa using an endo-cytoscopy system. Lung Cancer, 72(2), 184-190. doi:10.1016/j.lungcan.2010.08.006
  28. Nosaka, S., Kurimoto, N., & Morita, K. (2014). Endocytoscopy and Narrow Band Imaging for Super fi cial Extension of Squamous Cell Carcinoma. The Annals of Thoracic Surgery, 98(3), 1117. doi:10.1016/j.athoracsur.2014.05.053
  29. Scherübl, H., Jensen, R. T., Cadiot, G., Stölzel, U., & Klöppel, G. (2010). Neuroendocrine tumors of the small bowels are on the rise: Early aspects and management. World Journal of Gastrointestinal Endoscopy, 2(10), 325-334. doi:10.4253/wjge.v2.i10.325
  30. Ohigashi T (2006) In vivo observation of living bladder cancer cells using catheter-type contact ultra-magnifying endoscope UROLOGY 68 (Supplement 5A), November 2006, p.39
  31. Rao, G. V. (2007). Endocytoscopy assists in the intraoperative diagnosis of carcinoma in a patient with chronic pancreatitis. Endoscopy, 39, 317-318. doi:10.1055/s
  32. Rao, G. V., Mansard, M. J., Rebala, P., Sekaran, A., & Reddy, D. N. (2009). Endocytoscopy assisted laparoscopic intraoperative diagnosis of disseminated malignancy. Surgical Endoscopy and Other Interventional Techniques, 23, 2395-2396. doi:10.1007/s00464-009-0365-y
  33. Muto, M. (2007) Endoscopic Molecular Imaging of Gastrointestinal Neoplasm: A Pilot Study GASTROINTESTINAL ENDOSCOPY Volume 65, No. 5: 2007 AB 124
  34. Sumiyama, K., Tajiri, H., Kato, F., Imura, T., Ono, K., Ikeda, K., … Gostout, C. J. (2009). Pilot study for in vivo cellular imaging of the muscularis propria and ex vivo molecular imaging of myenteric neurons (with video). Gastrointestinal Endoscopy, 69(6), 1129-1134. doi:10.1016/j.gie.2008.08.007

Full text is published :
Pirogov S.S., Sokolov V.V., Kaprin A.V., Sokolov D.V. et al. ENDOCYTOSCOPY - NEW TYPE OF ENDOSCOPIC EXAMINATION OF LOWER GASTROINTESTINAL AND RESPIRATORY TRACT (PART 3). Experimental and Clinical Gastroenterology Journal. 2017;140(04):64-72
Read & Download full text

1. Peoples’ Friendship University of Russia (Moscow, Russian Federation)

Keywords:malignant large bowel obstruction,colorectal stenting,self-expanding metal stents,SEMS

Abstract:Literature review on colorectal stenting in malignant large bowel obstruction in comparison with surgery in different clinical situations supplemented by own retrospective analysis of stenting (56 patients) versus palliative surgery (50 patients) was performed. Stenting demonstrated lower levels of early complications (3,6 % / 22 %) and in-hospital mortality (1,8 % / 18 %) as compared with surgical palliation (p<0,01) with similar long-term results and therefore was recommended as preferred final palliation in incurable patients.

• References total 14 ⇓ :: .
  1. Dohmoto M., Rupp K. D., Hohlbach G. Endoscopically-implanted prosthesis in rectal carcinoma // Dtsch. Med. Wochenschr. - 1990. - Vol. 115 (23). - P. 915.
  2. Baron T. H., Wong Kee Song L. M., Repici A. Role of self-expandable stents for patients with colon cancer // Gastointest. Endosc. - 2012. - Vol. 75 (3). - P. 653-662.
  3. Pirlet I. A., Slim K., Kwiatkowski F., et al. Emergency preoperative stenting versus surgery for acute left-sided malignant colonic obstruction: a multicenter randomized controlled trial // Surg. Endosc. - 2011. - Vol. 25. - P. 1814-21.
  4. Van Hooft J. E., Bemelman W. A., Oldenburg B., et al. Colonic stenting versus emergency surgery for acute left-sided malignant colonic obstruction: a multicenter randomized study // Lancet Oncol. - 2011. - Vol. 12 (4). - P. 344-352.
  5. Alcántara M., Serra-Aracil X., Falcó J., et al. Prospective, controlled, randomized study of intraoperative colonic lavage versus stent placement in obstructive left-sided colonic cancer // World J. Surg. - 2011. - Vol. 35 (8). - P. 1904-1910.
  6. Huang X., Lv B., Zhang S., Meng L. Preoperative colonic stents versus emergency surgery for acute left-sided malignant colonic obstruction: a meta-analysis // J. Gastrointest. Surg. - 2014. - Vol. 18 (3). - P. 584-591.
  7. Gorissen K. J., Tuynman J. B., Fryer E., et al. Local recurrence after stenting for obstructing left-sided colonic cancer // Br. J. Surg. - 2013. - Vol. 100 (13). - P. 1805-1809.
  8. Sloothaak D. A.M., van den Berg M. W., Dijkgraaf M. G.W., et al. Oncological outcome of malignant colonic obstruction in the Dutch Stent-In 2 trial // Br. J. Surg. - 2014. - Vol. 101 (31). - P. 1751-1757.
  9. Van Hooft J. E., van Halsema E. E., Vanbiervliet G., et al. Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE) clinical guideline // Endoscopy. - 2014. - Vol. 46. - P. 990-1002.
  10. Matsuda A., Miyashita M., Matsumoto S., et al. Comparison of long-term outcomes of colonic stent as “bridge to surgery” and emergency surgery for malignant large-bowel obstruction: a meta-analysis // Ann. Surg. Oncol. - 2015. - Vol. 22 (2). - P. 497-504.
  11. Erichsen R., Horváth-Puhó E., Jacobsen J. B., et al. Long-term mortality and recurrence after colorectal cancer surgery with preoperative stenting: a Danish nationwide cohort study // Endoscopy. - 2015. - Vol. 47. - P. 517-524.
  12. Zhao X. D., Cai B. B., Cao R. S., Shi R. H. Palliative treatment for incurable malignant colorectal obstructions: a meta-analysis // World J. Gastroenterol. - 2013. - Vol. 19 (33). - P. 5565-5574.
  13. Liang T. W., Sun Y., Wei Y. C., Yang D. X. Palliative treatment of malignant colorectal obstruction caused by advanced malignancy: a self-expanding metallic stent or surgery? A system review and meta-analysis // Surg. Today. - 2014. - Vol. 44 (1). - P. 22-33.
  14. Takahashi H., Okabayashi K., Tsuruta M., et al. Self-expanding metallic stents versus surgical intervention as palliative therapy for obstructive colorectal cancer: a meta-analysis // World J. Surg. - 2015. - Vol. 39(8). - P. 2037-2044.

Full text is published :
Fedorov A.G., Davydova S.V., Klimov A.E. COLORECTAL STENTING VERSUS SURGERY IN MALIGNANT LARGE BOWEL OBSTRUCTION. Experimental and Clinical Gastroenterology Journal. 2017;140(04):73-75
Read & Download full text

1. Center of cosmetology and plastic surgery n. a. S. V. Nudelman (Moscow, Russian Federation)

Keywords:colonoscopy,cleansing,macrogol

Abstract:Based on the study results of 64 patients colonoscopy the use of brackish water “Longevity” solvent 15-20 % improvement in quality of preparation of the intestinal mucosa by colonoscopy when using traditional one-stage schemes with products based on macrogol, facilitates bowel cleansing in patients suffering from chronic constipation, and does not require increasing doses of drugs based on macrogol.

Full text is published :
Ivantsova M.A., Airapetov E.L., Oshchepkov V.A. THE USE OF BRACKISH WATER “LONGEVITY” AS A SOLVENT TO IMPROVE BOWEL CLEANSING FOR COLONOSCOPY. Experimental and Clinical Gastroenterology Journal. 2017;140(04):76-78
Read & Download full text