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EXPERIMENTAL GASTROENTEROLOGY

    1. N. V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department (Moscow, Russian Federation)

    Abstract: Objective: to study the effect of colistin on changes in the qualitative and quantitative composition of the cavity microflora of the jejunum and cecum in hypochlorhydria. Materials and Methods: The experiments were performed on 10 male rats of the Wistar line weighing 400-450 g. Under the conditions of hypochlorhydria caused by the pariet, the effect of intragastric administration of colistin on the cavity microflora of the jejunum and cecum was studied. Results. It has been shown that the administration of colistin for 7 days under hypochlorhydria conditions leads to changes in the composition of the microflora of the cecum and protects proximal sections of the small intestine from excessive colonization.

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    Full text is published :
    Tropskaya N.S., Shashkova I.G., Chernen’kaya T.V., Popova T.S. THE INFLUENCE OF SELECTIVE DECONTAMINATION OF GRAM-NEGATIVE FLORA ON INTESTINAL MICROBIOTA IN HYPOCHLORHYDRIA. Experimental and Clinical Gastroenterology Journal. 2017;147(11):92-95
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