1. Russian national research medical University n.a N. I. Pirogov

Keywords:biliary tract diseases,biliary sludge,cholelithiasis,gall bladder cholesterol,children

Abstract:This article describes the achievements in the study of diagnosis, treatment and prevention of diseases of the biliary tract in children, both from a historical point of view, and on the basis of the results of their own long-term research carried out at the Department, as well as students in different regions of Russia. New directions in the field of study of etiology, pathogenesis, clinic, diagnosis and treatment of biliary tract diseases in childhood with the introduction of new high-tech techniques are presented. The features of childhood do not allow to extrapolate some aspects of diagnosis and treatment tactics from adult practice to childhood. Based on more than 25 years of experience in monitoring and treatment of patients with various diseases of the biliary tract, new, fundamentally different approaches to the choice of diagnostic methods of research, therapeutic tactics of prevention and treatment at different stages of the disease are presented. All presented in the article of provisions is justified and evidence-based. Compliance with these directions will allow practitioners to improve the quality of life of patients and significantly reduce the disability of the child population.

• References total 9 ⇓ :: .
  1. Haritonova L. A. Zhelchnokamennaja bolezn' u detej (oso- bennosti patogeneza, kliniki, di agnostiki, lechenija) [Gall- stone disease in children (features of pathogenesis, clinics, diagnostics, treatment)] Avtoref. dis. dokt. med. nauk [Ab- stract. doct. med. sci. diss] Moscow, 1998. – 52p. (In Russian)
  2. Zaprudnov A.M., Kharitonova L. A. Biliarnaja patologi- ja u detej [Biliary pathology in children]. Moscow: MIA, 2008. – 376p.
  3. Novikov P. V. Nutrigenetika i nutrigenomika – novye naprav- lenija v nutriciologii v postgenomnyj period [Nutrige- netics and nutrigenomics: new trends in nutrition science in the postgenomic period]. Voprosy detskoj dietologoii. 2012;1:44–52.
  4. Klabukov I.D., Ljundup A.V, Djuzheva T. G., Tjaht A. V. Biliarnaja mikrobiota i zabolevanija zhelchnyh putej [Bil- iary Microbiota and Bile Duct Diseases]. Vestnik RAMN. 2017;72(3):172–179
  5. Lupash N. G. Zhelchnokamennaja bolezn' u detej rannego vozrasta (kliniko-patogenetic heskie, jepidemiologicheskie aspekty) [Gallstone disease in children of early age (clinical and pathogenetic, epidemiological aspects)]. Avtoref. dis. kand. med. nauk [Abstract. cand. med. sci. diss]. Moscow, 2005. – 37p.
  6. Barenbojm G.M., Chiganova M. A. Ksenobiotiki s lekarst- vennoj aktivnost'ju – novaja ugroza dlja okruzhajushhej sredy [Xenobiotics with drug activity are a new threat to the environme]. Trudy HIH Ros.nac.kongressa «Chelovek i lekarstvo» [Proc. XIXth Russian National Congress "Th e Man and the Medicine"]. Moscow, 2013, pp.12–27
  7. Potapova E.A., Haritonova L. A. Dislipidemii u detej s hole- litiazom, kak marker metabolicheskogo sindroma [Dyslip- idemia In Children With Cholelithiasis As A Marker Of Metabolic Syndrome]. Jeksperimental'naja i klinicheskaja gastronterologija [Experimen tal and Clinical gastroenter- ology]. 2014;101(1):35–38
  8. Car'kova O.N., Zaprudnov A. M., Haritonova L. A., Kosare- va T. M., Alekseeva Ju. E. Biliarnyj sladzh: kliniko–diag- nosticheskie i lechebno- profi lakticheskie aspekty [Biliary sludge: clinical, diagnostic, therapeutic and preventive aspects] Ros. vest. perinatologii i pediatrii. 2009;6:38–42
  9. Zaprudnov A.M., Bogomaz L. V., Haritonova L. A., Ko sa re- va T. M., Car'kova O. N. Znachenie metodov medicinskoj intraskopii v diagnostike zabolevanij biliarnogo trakta u detej [Signifi cance of medical introscopy methods in the diagnosis of biliary tract di seases in children]. Vestnik ros. gos. med. universiteta. 2010;6:36–39

Full text is published :
ADVANCES IN THE STUDY OF DISEASES BILIARY TRACT IN CHILDHOOD. Experimental and Clinical Gastroenterology Journal. 2018;149(01):04-13
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