1. Federal State Budget Educational Institution of Higher Education “Novosibirsk State Medical University” of the Ministry of Heal th of Russia (FSBEI HE NSMU MOH Russia) (630091, Novosibirsk, Russia)
2. GBUZ NSO “State Novosibirsk Regional Clinical Hospital” (630087, Novosibirsk, Russia)

Keywords: rocuronium, obesity, body surface area

Abstract:The qualitative indicators of the neuromuscular block were compared and evaluated the heart rate variability, using a variety of the methods of dosing of rocuronium bromide in th e female patients with BMI more than 40 kg∙m-2, who were operated by laparoscopic cholelithiasis. It has been determined that the dosage of rocuronium bromide 30 mg / m² on the body surface area has an advantage over dosing on the ideal body weight, reduces sympathotony, the temporary ranges of the block duration and the need for re peated administration of rocuronium bromide. There was an expressed correlation between the amount of the entered rocuro nium and the stress index of heart rate in the calculation on the body surface area than on the body weight. It allows to suggest more security on the dosing on the surface area than on the weight.

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Full text is published :
Shmakov A. N., Elizareva N. L., Kolosov A. N., Kokhno V. N., Loktin E. M. Dosage of rocurony to the surface of the body surfa ce of patients with morbid obesity. Experimental and Clinical Gastroenterology. 2018;155(7): 124–127.
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1. Orenburg regional hospital No 1 (Orenburg, Russia)
2. Orenburg State Medical University (Orenburg, Russia)

Keywords: ileocecal valve, endoscopic anatomy

Abstract:Objective : to improve the diagnosis and treatment of diseases of the ileocecal section. To improve the diagnosis and possible operative and endosc opic treatment of the ileocecal section, knowledge of normal anatomy and clinical anatomy is necessary. Much attent ion is paid to the state of the valvular apparatus of the gastrointestinal tract in normal and with various pathologies, an d in particular, the ileocecal section, both in adults and in children. The following intravital methods for diagnosing the condition of the ileocec al section are available: X-ray, endo- scopic, functional — peripheral computer electrogastroenterography. Conclusions . The presented literature data testify to the gr eat functional signifi cance of the ileocecal section both for the gas- trointestinal tract and for the entire human body as a whole. But the available endoscopic data is fragmentary, illuminates the individual elements of the transition, is not systematized. Thus, the infor mation presented in the review of the literature ind icates the relevance and expediency of studying the endoscopic anatomy of the ileocecal section both in normal and in some diseases.

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Full text is published :
Shepelev A. N., Dronova O. B., Fateev I. N., Petrov S. V., Ne verov A. N. Endoscopic anatomy of the ileocectal department and its clinical value. Experimental and Clinical Gastroenterology. 2018;155(7): 128–134.
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1. JSC “Group of companies “MEDSI”
2. Federal Research & Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency
3. RUDN University (117198, Moscow, Russia)

Abstract:The aim of the study was to evaluate the eff ectiveness and safety of sodium phosphate (NaP) for colon cleaning in clinical practice. Patients and methods : 63 patients were under observation. Of these, 32 took the tablet form of Na P. The control group consisted of 31 patients who were preparing for colonoscop y using the standard method using a two-regimen for prepa- ration of polyethylene glycol 4000. Conditions for the use of th e NaP-tablet form were evaluated using a scale of criteria for compliance with the recommended treatment regimen. Results . Adequate use of the tablet form of NaP was noted in 84% of patients. The main reasons for the inadequate training were non-compliance with the intake of 1 person (3.1%), no n-compliance with the diet be fore preparation for the study — 3 people (9.4%).Evaluation of the quality of preparat ion for the study was carried out accord ing to the Boston scale [1–3]. When esophagogastroduodenoscopy was carried out, 34.3% (11 patien ts) of patients showed changes in gastric mucosae of the stomach, of which possible association with the reception of th e tablet form of NaP in 1 (3.1%). Drug withdrawal and prepa- ration for study 1 (3.1%) were stopped. The compliance with the use of the tablet form of NaP was high, especially among patients who previously used other prep arations for intestinal preparation. Conclusions : the use of the tablet form of NaP in preparing the colon for colonoscop y when compared with other methods of purifi cation showed good results both in the quality of th e patient’s preparation and in th e continuity of the patients with this preparation in preparation and in the safety of its use, which coincides wi th the data of other randomized research.

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Full text is published :
Shcherbakov P. L., Kalachnyuk T. N., Ivanova O. I., Arkhipov A. A.et al. The fi rst clinical expe rience of using the tableted form of sodium phosphate (NAP) colokit, when preparing for colonoscopy in Russia. Experimental and Clinical Gastroenterology . 2018;155(7): 135–141.
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