1. Pirogov Medical University, Moscow, Russia
2. State Clinical hospital № 29 them. Baumann, Моscow, Russia

Keywords: microbiota, obesity, dyslipidemia

Abstract: The gut microbiota has attracted increasing attention during the last several years as a key player in the pathophysiology of chronic disease. Microbiome is considered to be the link between metabolic disorders, obesity, insulin resistance, dyslipidemia, diabetes, hypertension and cardiovascular diseases. Recent findings have related the intestinal microbiota to a plethora of pathological conditions, including type 2 diabetes, obesity, cholelithiasis and nonalcoholic steatohepatitis. This review presents potential mechanisms for the development of these diseases in response to changes in the gut microbiota. They involve increased gut permeability, low-grade inflammation and autoantibodies. Many studies contradict each other, which confirms the need for further scientific research in this area.

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Full text is published :
Kharitonova L. A., Papisheva О. V., Mayatskaya T. A., Kotaysh G. A. State of the micro-biota of bowels with dislipidemii in the children. Experimental and Clinical Gastroenterology. 2019;171(11): 76–82. (In Russ.) DOI: 10.31146/1682-8658-ecg-171-11-76-82
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