1. Russian National Research Medical University N. I. Pirogov, Ministry of Health of Russia, Moscow, Russia, 1 Ostrovityanova st. Moscow 117997
2. Children΄s City Clinical Hospital Z. A. Bashlyaevoy, 28 Heroes of Panfi lov st Moscow 125373

Keywords: Albendazole, drug- induced liver injury, liver, drug, children

Abstract: A case of the drug-induced liver injury (DILI) development is presented on the background of the self-treatment with an antiparasitic drug Albendazole in an 11 years-old girl with several risk factors for the drug-induced liver injury (history of a drug reaction, carbohydrate and fat metabolism disturbance, female gender, and adolescence). The disease was diagnosed using the the CIOMS/RUCAM scale. The drug was withdrawn and the pathogenetic therapy was established (fluids, hepatoprotective drugs) with the resolution of the drug-induced hepatitis.

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Full text is published :
Borzakova S. N., Kharitonova L. A., Ermakova M. N., Osmanov I. M., Rudikova E. V. Albendazole-induced liver injury of a 11-year-old girl. Experimental and Clinical Gastroenterology. 2019;171(11): 83–88. (In Russ.) DOI: 10.31146/1682-8658-ecg-171-11-83-88
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1. FGBOU IN RNIMU them. N. I. Pirogova of the Ministry of Health of Russia, 117997, Moscow, Russia
2. RCCH FSBEI IN RNIMU them. N. I. Pirogova of the Ministry of Health of Russia, 119571, Moscow, Russia

Keywords: cystic fi brosis, food allergy, sensitization of children

Abstract: Cystic fibrosis is a hereditary disease that affects the quality of life of patients without proper treatment. It has been established that allergic diseases have become a global public health problem. Due to a variety of clinical manifestations that affect the development, health and quality of life, it is difficult to diagnose. Due to the high incidence of allergic problems, there is the problem of interrelationship of hereditary genetic diseases - cystic fibrosis and spectral sensitization of children suffering from morbidity in order to improve the algorithms, improve the condition and quality of life of patients, due to the appointment of proper diet therapy.

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Full text is published :
Antonova E. A., Goryainova A. V., Semykin S. Yu., Filatova T. A. The spectrum of sensitization of children with cystic fi brosis. Experimental and Clinical Gastroenterology. 2019;171(11): 89–92. (In Russ.) DOI: 10.31146/1682-8658-ecg-171-11-89-92
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1. Saratov State Medical University, n. a. V. I. Razumovsky of the Ministry of Health of Russia, Russia, Saratov, B .Kazachja, 112, 410012

Keywords: peptic ulcer, symptomatic ulcer, complications of peptic ulcer, prepyloric stenosis

Abstract: In the article, the authors present brief information about gastric ulcer and duodenal ulcer, its epidemiology, diagnostic capabilities, approaches to the treatment and prevention of complications. In addition, there are data on the diagnosis and verification of symptomatic gastroduodenal ulcers. Using the example of a clinical case of a complicated symptomatic ulcer in a child, the authors describe the difficulties encountered at the stages of diagnosis, treatment, and follow-up at high risk of complications.

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Full text is published :
Spivakovskiy Yu. M., Spivakovsky A. Yu., Chernenkov Yu. V., Volkova O. V., Goremykina I. V., Dushanova A. K. The case of atypical course of gastric ulcer in pediatric practice. Experimental and Clinical Gastroenterology. 2019;171(11): 93–99. (In Russ.) DOI: 10.31146/1682-8658-ecg-171-11-93-99
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