1. Федеральное государственное бюджетное образовательное учреждение высшего образования «Саратовский государственный медицинский университет имени В. И. Разумовского» Министерства здравоохранения Российской Федерации (410012, г. Саратов, Россия)

Ключевые слова: М2-пируваткина, матриксные металлопротеиназы (ММП), кальпротектин, лактоферрин, антинейтрофильные цитоплазматические антитела (ANCA), анти-Saccharomyces cerevisae антитела (ASCA)

Резюме: Распространенность воспалительных заболеваний кишечника (ВЗК) (язвенного колита (ЯК) и болезни Крона (БК)) ежегодно увеличивается. Актуальными остаются проблемы ранней и неинвазивной диагностики ВЗК. Цель настоящего обзора — анализ диагностической ценности различных биологических маркеров ВЗК. Основная цель поиска новых биомаркеров ВЗК заключена в возможности минимизировать повторные эндоскопические исследования для ранней диагностики и определения активности заболевания, оценки эффективности лечения и профилактики осложнений. Представлены широко используемые, рутинные, а также перспективные биологические маркеры, позволяющие верифицировать диагноз ВЗК, оценить течение и прогноз болезни.

• Литература всего 45 ⇓ :: .
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Для цитирования :
Козлова И. В., Кудишина М. М., Пахомова А. Л. Биомаркеры воспалительных заболеваний кишечника. Экспериментальная и клиническая гастроэнтерология. 2018;157(9): 4–9. DOI: 10.31146/1682-8658-ecg-157-9-4-9.
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